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Polycythemia vera is not initiated by JAK2V617F mutation.
Nussenzveig RH, Swierczek SI, Jelinek J, Gaikwad A, Liu E, Verstovsek S, Prchal JF, Prchal JT. Nussenzveig RH, et al. Among authors: gaikwad a. Exp Hematol. 2007 Jan;35(1):32-8. doi: 10.1016/j.exphem.2006.11.012. Exp Hematol. 2007. PMID: 17198871 Free article.
Missense mutation of the last nucleotide of exon 1 (G->C) of beta globin gene not only leads to undetectable mutant peptide and transcript but also interferes with the expression of wild allele.
Agarwal N, Kutlar F, Mojica-Henshaw MP, Ou CN, Gaikwad A, Reading NS, Bailey L, Kutlar A, Prchal JT. Agarwal N, et al. Among authors: gaikwad a. Haematologica. 2007 Dec;92(12):1715-6. doi: 10.3324/haematol.11543. Haematologica. 2007. PMID: 18056002 Free article.
Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor.
Quintás-Cardama A, Manshouri T, Estrov Z, Harris D, Zhang Y, Gaikwad A, Kantarjian HM, Verstovsek S. Quintás-Cardama A, et al. Among authors: gaikwad a. Invest New Drugs. 2011 Oct;29(5):818-26. doi: 10.1007/s10637-010-9429-z. Epub 2010 Apr 7. Invest New Drugs. 2011. PMID: 20372971 Free PMC article.
424 results