Dent P - Search Results

1

Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.

Fisher PB, Sarkar D, Lebedeva IV, Emdad L, Gupta P, Sauane M, Su ZZ, Grant S, Dent P, Curiel DT, Senzer N, Nemunaitis J. Fisher PB, et al. Among authors: dent p. Toxicol Appl Pharmacol. 2007 Nov 1;224(3):300-7. doi: 10.1016/j.taap.2006.11.021. Epub 2006 Nov 23. Toxicol Appl Pharmacol. 2007. PMID: 17208263 Free PMC article. Review.

2

mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Valerie K, Dent P, Fisher PB. Sarkar D, et al. Among authors: dent p. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10054-9. doi: 10.1073/pnas.152327199. Epub 2002 Jul 11. Proc Natl Acad Sci U S A. 2002. PMID: 12114539 Free PMC article.

3

mda-7 (IL-24): signaling and functional roles.

Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Dent P, Fisher PB. Sarkar D, et al. Among authors: dent p. Biotechniques. 2002 Oct;Suppl:30-9. Biotechniques. 2002. PMID: 12395925

4

MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine.

Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Lebedeva IV, Dent P, Pestka S, Fisher PB. Sauane M, et al. Among authors: dent p. Cytokine Growth Factor Rev. 2003 Feb;14(1):35-51. doi: 10.1016/s1359-6101(02)00074-6. Cytokine Growth Factor Rev. 2003. PMID: 12485618 Review.

5

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Su ZZ, Lebedeva IV, Sarkar D, Gopalkrishnan RV, Sauane M, Sigmon C, Yacoub A, Valerie K, Dent P, Fisher PB. Su ZZ, et al. Among authors: dent p. Oncogene. 2003 Feb 27;22(8):1164-80. doi: 10.1038/sj.onc.1206062. Oncogene. 2003. PMID: 12606943

6

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways.

Sauane M, Gopalkrishnan RV, Lebedeva I, Mei MX, Sarkar D, Su ZZ, Kang DC, Dent P, Pestka S, Fisher PB. Sauane M, et al. Among authors: dent p. J Cell Physiol. 2003 Aug;196(2):334-45. doi: 10.1002/jcp.10309. J Cell Physiol. 2003. PMID: 12811827

7

mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.

Fisher PB, Gopalkrishnan RV, Chada S, Ramesh R, Grimm EA, Rosenfeld MR, Curiel DT, Dent P. Fisher PB, et al. Among authors: dent p. Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S23-37. Cancer Biol Ther. 2003. PMID: 14508078 Review.

8

Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.

Lebedeva IV, Sarkar D, Su ZZ, Kitada S, Dent P, Stein CA, Reed JC, Fisher PB. Lebedeva IV, et al. Among authors: dent p. Oncogene. 2003 Nov 27;22(54):8758-73. doi: 10.1038/sj.onc.1206891. Oncogene. 2003. PMID: 14647471

9

Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.

Lebedeva IV, Su ZZ, Sarkar D, Kitada S, Dent P, Waxman S, Reed JC, Fisher PB. Lebedeva IV, et al. Among authors: dent p. Cancer Res. 2003 Dec 1;63(23):8138-44. Cancer Res. 2003. PMID: 14678967

10

Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways.

Sauane M, Lebedeva IV, Su ZZ, Choo HT, Randolph A, Valerie K, Dent P, Gopalkrishnan RV, Fisher PB. Sauane M, et al. Among authors: dent p. Cancer Res. 2004 May 1;64(9):2988-93. doi: 10.1158/0008-5472.can-04-0200. Cancer Res. 2004. PMID: 15126330

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