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The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport.
Solinas M, Tanda G, Justinova Z, Wertheim CE, Yasar S, Piomelli D, Vadivel SK, Makriyannis A, Goldberg SR. Solinas M, et al. Among authors: piomelli d. J Pharmacol Exp Ther. 2007 Apr;321(1):370-80. doi: 10.1124/jpet.106.114124. Epub 2007 Jan 8. J Pharmacol Exp Ther. 2007. PMID: 17210800 Free article.
Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats.
Scherma M, Panlilio LV, Fadda P, Fattore L, Gamaleddin I, Le Foll B, Justinová Z, Mikics E, Haller J, Medalie J, Stroik J, Barnes C, Yasar S, Tanda G, Piomelli D, Fratta W, Goldberg SR. Scherma M, et al. Among authors: piomelli d. J Pharmacol Exp Ther. 2008 Nov;327(2):482-90. doi: 10.1124/jpet.108.142224. Epub 2008 Aug 25. J Pharmacol Exp Ther. 2008. PMID: 18725543 Free PMC article.
The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition.
Scherma M, Medalie J, Fratta W, Vadivel SK, Makriyannis A, Piomelli D, Mikics E, Haller J, Yasar S, Tanda G, Goldberg SR. Scherma M, et al. Among authors: piomelli d. Neuropharmacology. 2008 Jan;54(1):129-40. doi: 10.1016/j.neuropharm.2007.08.011. Epub 2007 Aug 19. Neuropharmacology. 2008. PMID: 17904589 Free PMC article.
The endocannabinoid system in brain reward processes.
Solinas M, Goldberg SR, Piomelli D. Solinas M, et al. Among authors: piomelli d. Br J Pharmacol. 2008 May;154(2):369-83. doi: 10.1038/bjp.2008.130. Epub 2008 Apr 14. Br J Pharmacol. 2008. PMID: 18414385 Free PMC article. Review.
Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats.
Panlilio LV, Thorndike EB, Nikas SP, Alapafuja SO, Bandiera T, Cravatt BF, Makriyannis A, Piomelli D, Goldberg SR, Justinova Z. Panlilio LV, et al. Among authors: piomelli d. Psychopharmacology (Berl). 2016 May;233(10):1879-88. doi: 10.1007/s00213-015-4140-6. Epub 2015 Nov 12. Psychopharmacology (Berl). 2016. PMID: 26558620 Free PMC article.
Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse.
Justinova Z, Panlilio LV, Moreno-Sanz G, Redhi GH, Auber A, Secci ME, Mascia P, Bandiera T, Armirotti A, Bertorelli R, Chefer SI, Barnes C, Yasar S, Piomelli D, Goldberg SR. Justinova Z, et al. Among authors: piomelli d. Neuropsychopharmacology. 2015 Aug;40(9):2185-97. doi: 10.1038/npp.2015.62. Epub 2015 Mar 10. Neuropsychopharmacology. 2015. PMID: 25754762 Free PMC article.
451 results