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The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport.
Solinas M, Tanda G, Justinova Z, Wertheim CE, Yasar S, Piomelli D, Vadivel SK, Makriyannis A, Goldberg SR. Solinas M, et al. Among authors: tanda g. J Pharmacol Exp Ther. 2007 Apr;321(1):370-80. doi: 10.1124/jpet.106.114124. Epub 2007 Jan 8. J Pharmacol Exp Ther. 2007. PMID: 17210800
The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition.
Scherma M, Medalie J, Fratta W, Vadivel SK, Makriyannis A, Piomelli D, Mikics E, Haller J, Yasar S, Tanda G, Goldberg SR. Scherma M, et al. Among authors: tanda g. Neuropharmacology. 2008 Jan;54(1):129-40. doi: 10.1016/j.neuropharm.2007.08.011. Epub 2007 Aug 19. Neuropharmacology. 2008. PMID: 17904589 Free PMC article.
Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats.
Scherma M, Panlilio LV, Fadda P, Fattore L, Gamaleddin I, Le Foll B, Justinová Z, Mikics E, Haller J, Medalie J, Stroik J, Barnes C, Yasar S, Tanda G, Piomelli D, Fratta W, Goldberg SR. Scherma M, et al. Among authors: tanda g. J Pharmacol Exp Ther. 2008 Nov;327(2):482-90. doi: 10.1124/jpet.108.142224. Epub 2008 Aug 25. J Pharmacol Exp Ther. 2008. PMID: 18725543 Free PMC article.
123 results