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Page 1
Endothelin receptor antagonists.
Clozel M, Maresta A, Humbert M. Clozel M, et al. Handb Exp Pharmacol. 2013;218:199-227. doi: 10.1007/978-3-642-38664-0_9. Handb Exp Pharmacol. 2013. PMID: 24092342 Review.
Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.
Bolli MH, Marfurt J, Grisostomi C, Boss C, Binkert C, Hess P, Treiber A, Thorin E, Morrison K, Buchmann S, Bur D, Ramuz H, Clozel M, Fischli W, Weller T. Bolli MH, et al. Among authors: clozel m. J Med Chem. 2004 May 20;47(11):2776-95. doi: 10.1021/jm031115r. J Med Chem. 2004. PMID: 15139756
The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonist.
Bolli MH, Boss C, Binkert C, Buchmann S, Bur D, Hess P, Iglarz M, Meyer S, Rein J, Rey M, Treiber A, Clozel M, Fischli W, Weller T. Bolli MH, et al. Among authors: clozel m. J Med Chem. 2012 Sep 13;55(17):7849-61. doi: 10.1021/jm3009103. Epub 2012 Aug 16. J Med Chem. 2012. PMID: 22862294
Bis-sulfonamides as endothelin receptor antagonists.
Boss C, Bolli MH, Weller T, Fischli W, Clozel M. Boss C, et al. Among authors: clozel m. Bioorg Med Chem Lett. 2003 Mar 10;13(5):951-4. doi: 10.1016/s0960-894x(02)01083-1. Bioorg Med Chem Lett. 2003. PMID: 12617928
146 results