Bertino JR - Search Results

1

Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.

Lin JT, Tong WP, Trippett TM, Niedzwiecki D, Tao Y, Tan C, Steinherz P, Schweitzer BI, Bertino JR. Lin JT, et al. Among authors: bertino jr. Leuk Res. 1991;15(12):1191-6. doi: 10.1016/0145-2126(91)90189-z. Leuk Res. 1991. PMID: 1722550

2

The basis for intrinsic drug resistance or sensitivity to methotrexate.

Bertino JR, Lin J, Pizzorno G, Li WW, Chang YM. Bertino JR, et al. Adv Enzyme Regul. 1989;29:277-85. doi: 10.1016/0065-2571(89)90107-6. Adv Enzyme Regul. 1989. PMID: 2633614

3

Increased activity of gamma-glutamyl hydrolase in human sarcoma cell lines: a novel mechanism of intrinsic resistance to methotrexate (MTX).

Li WW, Waltham M, Tong W, Schweitzer BI, Bertino JR. Li WW, et al. Among authors: bertino jr. Adv Exp Med Biol. 1993;338:635-8. doi: 10.1007/978-1-4615-2960-6_131. Adv Exp Med Biol. 1993. PMID: 7508171 No abstract available.

4

Acute monocytic leukemia: a myeloid leukemia subset that may be sensitive to methotrexate.

Göker E, Kheradpour A, Waltham M, Banerjee D, Tong WP, Elisseyeff Y, Bertino JR. Göker E, et al. Among authors: bertino jr. Leukemia. 1995 Feb;9(2):274-6. Leukemia. 1995. PMID: 7532768

5

Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease.

Göker E, Lin JT, Trippett T, Elisseyeff Y, Tong WP, Niedzwiecki D, Tan C, Steinherz P, Schweitzer BI, Bertino JR. Göker E, et al. Among authors: bertino jr. Leukemia. 1993 Jul;7(7):1000-4. Leukemia. 1993. PMID: 7686600

6

A phase II study of continuous infusion of trimetrexate in patients with refractory acute leukemia.

Kheradpour A, Berman E, Göker E, Lin JT, Tong WP, Bertino JR. Kheradpour A, et al. Among authors: bertino jr. Cancer Invest. 1995;13(1):36-40. doi: 10.3109/07357909509024893. Cancer Invest. 1995. PMID: 7834472 Clinical Trial.

7

Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression.

Gorlick R, Goker E, Trippett T, Steinherz P, Elisseyeff Y, Mazumdar M, Flintoff WF, Bertino JR. Gorlick R, et al. Among authors: bertino jr. Blood. 1997 Feb 1;89(3):1013-8. Blood. 1997. PMID: 9028333 Free article.

8

Increased methotrexate polyglutamylation in acute megakaryocytic leukemia (M7) compared to other subtypes of acute myelocytic leukemia.

Argiris A, Longo GS, Gorlick R, Tong W, Steinherz P, Bertino JR. Argiris A, et al. Among authors: bertino jr. Leukemia. 1997 Jun;11(6):886-9. doi: 10.1038/sj.leu.2400647. Leukemia. 1997. PMID: 9177445

9

gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.

Longo GS, Gorlick R, Tong WP, Lin S, Steinherz P, Bertino JR. Longo GS, et al. Among authors: bertino jr. Oncol Res. 1997;9(5):259-63. Oncol Res. 1997. PMID: 9306433

10

Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate.

Li WW, Tong WP, Bertino JR. Li WW, et al. Among authors: bertino jr. Clin Cancer Res. 1995 Jun;1(6):631-6. Clin Cancer Res. 1995. PMID: 9816025

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