Allen MP - Search Results

1

Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.

Chappie TA, Humphrey JM, Allen MP, Estep KG, Fox CB, Lebel LA, Liras S, Marr ES, Menniti FS, Pandit J, Schmidt CJ, Tu M, Williams RD, Yang FV. Chappie TA, et al. Among authors: allen mp. J Med Chem. 2007 Jan 25;50(2):182-5. doi: 10.1021/jm060653b. J Med Chem. 2007. PMID: 17228859

2

Biaryl piperidines as potent and selective delta opioid receptor ligands.

Liras S, McHardy SF, Allen MP, Segelstein BE, Heck SD, Bryce DK, Schmidt AW, Vanase-Frawley M, Callegari E, McLean S. Liras S, et al. Among authors: allen mp. Bioorg Med Chem Lett. 2010 Jan 15;20(2):503-7. doi: 10.1016/j.bmcl.2009.11.113. Epub 2009 Nov 26. Bioorg Med Chem Lett. 2010. PMID: 20015649

3

Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel mu opioid receptor ligands.

Allen MP, Blake JF, Bryce DK, Haggan ME, Liras S, McLean S, Segelstein BE. Allen MP, et al. Bioorg Med Chem Lett. 2000 Mar 20;10(6):523-6. doi: 10.1016/s0960-894x(00)00034-2. Bioorg Med Chem Lett. 2000. PMID: 10741545

4

Ring closing metathesis mediated synthesis of 4a-aryloxodecahydroisoquinolines, intermediates in the preparation of novel opiates.

Liras S, Allen MP, Blake JF. Liras S, et al. Among authors: allen mp. Org Lett. 2001 Nov 1;3(22):3483-6. doi: 10.1021/ol016588b. Org Lett. 2001. PMID: 11678688

5

Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group.

Erion MD, Niwas S, Rose JD, Ananthan S, Allen M, Secrist JA 3rd, Babu YS, Bugg CE, Guida WC, Ealick SE, et al. Erion MD, et al. J Med Chem. 1993 Nov 26;36(24):3771-83. doi: 10.1021/jm00076a004. J Med Chem. 1993. PMID: 8254607

6

ATP-citrate lyase as a target for hypolipidemic intervention. Design and synthesis of 2-substituted butanedioic acids as novel, potent inhibitors of the enzyme.

Gribble AD, Dolle RE, Shaw A, McNair D, Novelli R, Novelli CE, Slingsby BP, Shah VP, Tew D, Saxty BA, Allen M, Groot PH, Pearce N, Yates J. Gribble AD, et al. J Med Chem. 1996 Aug 30;39(18):3569-84. doi: 10.1021/jm960167w. J Med Chem. 1996. PMID: 8784456

7

Validation of screening immobilized peptide libraries for discovery of protease substrates.

Singh J, Allen MP, Ator MA, Gainor JA, Whipple DA, Solowiej JE, Treasurywala AM, Morgan BA, Gordon TD, Upson DA. Singh J, et al. Among authors: allen mp. J Med Chem. 1995 Jan 20;38(2):217-9. doi: 10.1021/jm00002a001. J Med Chem. 1995. PMID: 7830262 No abstract available.

8

Lead development: validation and application of high throughput screening for determination of pharmacokinetic parameters for enzyme inhibitors.

Singh J, Soloweij J, Allen M, Killar L, Ator M. Singh J, et al. Bioorg Med Chem. 1996 May;4(5):639-43. doi: 10.1016/0968-0896(96)00057-0. Bioorg Med Chem. 1996. PMID: 8804527

9

Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer.

Zhang Y, Seigal BA, Terrett NK, Talbott RL, Fargnoli J, Naglich JG, Chaudhry C, Posy SL, Vuppugalla R, Cornelius G, Lei M, Wang C, Zhang Y, Schmidt RJ, Wei DD, Miller MM, Allen MP, Li L, Carter PH, Vite GD, Borzilleri RM. Zhang Y, et al. Among authors: allen mp. ACS Med Chem Lett. 2015 May 27;6(7):770-5. doi: 10.1021/acsmedchemlett.5b00091. eCollection 2015 Jul 9. ACS Med Chem Lett. 2015. PMID: 26191364 Free PMC article.

10

CITU: A Peptide and Decarboxylative Coupling Reagent.

deGruyter JN, Malins LR, Wimmer L, Clay KJ, Lopez-Ogalla J, Qin T, Cornella J, Liu Z, Che G, Bao D, Stevens JM, Qiao JX, Allen MP, Poss MA, Baran PS. deGruyter JN, et al. Among authors: allen mp. Org Lett. 2017 Nov 17;19(22):6196-6199. doi: 10.1021/acs.orglett.7b03121. Epub 2017 Nov 8. Org Lett. 2017. PMID: 29115835 Free PMC article.

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