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Multiple myeloma-reactive T cells recognize an activation-induced minor histocompatibility antigen encoded by the ATP-dependent interferon-responsive (ADIR) gene.
van Bergen CA, Kester MG, Jedema I, Heemskerk MH, van Luxemburg-Heijs SA, Kloosterboer FM, Marijt WA, de Ru AH, Schaafsma MR, Willemze R, van Veelen PA, Falkenburg JH. van Bergen CA, et al. Blood. 2007 May 1;109(9):4089-96. doi: 10.1182/blood-2006-08-043935. Epub 2007 Jan 18. Blood. 2007. PMID: 17234742 Free article. Clinical Trial.
High-throughput characterization of 10 new minor histocompatibility antigens by whole genome association scanning.
Van Bergen CA, Rutten CE, Van Der Meijden ED, Van Luxemburg-Heijs SA, Lurvink EG, Houwing-Duistermaat JJ, Kester MG, Mulder A, Willemze R, Falkenburg JH, Griffioen M. Van Bergen CA, et al. Among authors: van luxemburg heijs sa. Cancer Res. 2010 Nov 15;70(22):9073-83. doi: 10.1158/0008-5472.CAN-10-1832. Epub 2010 Nov 9. Cancer Res. 2010. PMID: 21062987
Identification of a coordinated CD8 and CD4 T cell response directed against mismatched HLA Class I causing severe acute graft-versus-host disease.
Amir AL, Hagedoorn RS, van Luxemburg-Heijs SA, Marijt EW, Kruisselbrink AB, Frederik Falkenburg JH, Heemskerk MH. Amir AL, et al. Among authors: van luxemburg heijs sa. Biol Blood Marrow Transplant. 2012 Feb;18(2):210-9. doi: 10.1016/j.bbmt.2011.10.018. Epub 2011 Oct 19. Biol Blood Marrow Transplant. 2012. PMID: 22015995 Free article. Clinical Trial.
Identification of 4 novel HLA-B*40:01 restricted minor histocompatibility antigens and their potential as targets for graft-versus-leukemia reactivity.
Griffioen M, Honders MW, van der Meijden ED, van Luxemburg-Heijs SA, Lurvink EG, Kester MG, van Bergen CA, Falkenburg JH. Griffioen M, et al. Among authors: van luxemburg heijs sa. Haematologica. 2012 Aug;97(8):1196-204. doi: 10.3324/haematol.2011.049478. Epub 2012 Mar 14. Haematologica. 2012. PMID: 22419570 Free PMC article.
Patient HLA-DP-specific CD4+ T cells from HLA-DPB1-mismatched donor lymphocyte infusion can induce graft-versus-leukemia reactivity in the presence or absence of graft-versus-host disease.
Rutten CE, van Luxemburg-Heijs SA, Halkes CJ, van Bergen CA, Marijt EW, Oudshoorn M, Griffioen M, Falkenburg JH. Rutten CE, et al. Among authors: van luxemburg heijs sa. Biol Blood Marrow Transplant. 2013 Jan;19(1):40-8. doi: 10.1016/j.bbmt.2012.07.020. Epub 2012 Aug 4. Biol Blood Marrow Transplant. 2013. PMID: 22871556 Free article. Clinical Trial.
HLA class II upregulation during viral infection leads to HLA-DP-directed graft-versus-host disease after CD4+ donor lymphocyte infusion.
Stevanovic S, van Bergen CA, van Luxemburg-Heijs SA, van der Zouwen B, Jordanova ES, Kruisselbrink AB, van de Meent M, Harskamp JC, Claas FH, Marijt EW, Zwaginga JJ, Halkes CJ, Jedema I, Griffioen M, Falkenburg JH. Stevanovic S, et al. Among authors: van luxemburg heijs sa. Blood. 2013 Sep 12;122(11):1963-73. doi: 10.1182/blood-2012-12-470872. Epub 2013 Jun 18. Blood. 2013. PMID: 23777765 Free article. Clinical Trial.
Direct cloning of leukemia-reactive T cells from patients treated with donor lymphocyte infusion shows a relative dominance of hematopoiesis-restricted minor histocompatibility antigen HA-1 and HA-2 specific T cells.
Kloosterboer FM, van Luxemburg-Heijs SA, van Soest RA, Barbui AM, van Egmond HM, Strijbosch MP, Kester MG, Marijt WA, Goulmy E, Willemze R, Falkenburg JH. Kloosterboer FM, et al. Leukemia. 2004 Apr;18(4):798-808. doi: 10.1038/sj.leu.2403297. Leukemia. 2004. PMID: 14973499
40 results