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Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells.
Hyrcza MD, Kovacs C, Loutfy M, Halpenny R, Heisler L, Yang S, Wilkins O, Ostrowski M, Der SD. Hyrcza MD, et al. Among authors: loutfy m. J Virol. 2007 Apr;81(7):3477-86. doi: 10.1128/JVI.01552-06. Epub 2007 Jan 24. J Virol. 2007. PMID: 17251300 Free PMC article.
Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo.
Nie Z, Bren GD, Vlahakis SR, Schimnich AA, Brenchley JM, Trushin SA, Warren S, Schnepple DJ, Kovacs CM, Loutfy MR, Douek DC, Badley AD. Nie Z, et al. Among authors: loutfy mr. J Virol. 2007 Jul;81(13):6947-56. doi: 10.1128/JVI.02798-06. Epub 2007 Apr 18. J Virol. 2007. PMID: 17442709 Free PMC article.
Randomized controlled trial of once-daily tenofovir, lamivudine, and lopinavir/ritonavir versus remaining on the same regimen in virologically suppressed HIV-infected patients on their first PI-containing HAART regimen.
Loutfy MR, Ackad N, Antoniou T, Baril JG, Conway B, de Wet J, Trottier B, Kovacs CM, Thompson W, Martel AY, Trottier S, Rouleau D, Shafran SD, Rachlis A, Fraser C, Smaill F, Walmsley SL, Tseng AL, Sampalis JS. Loutfy MR, et al. HIV Clin Trials. 2007 Sep-Oct;8(5):259-68. doi: 10.1310/hct0805-259. HIV Clin Trials. 2007. PMID: 17956827 Clinical Trial.
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