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Diazenedicarboxamides as inhibitors of D-alanine-D-alanine ligase (Ddl).
Kovac A, Majce V, Lenarsic R, Bombek S, Bostock JM, Chopra I, Polanc S, Gobec S. Kovac A, et al. Among authors: chopra i. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2047-54. doi: 10.1016/j.bmcl.2007.01.015. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17267218
A de novo designed inhibitor of D-Ala-D-Ala ligase from E. coli.
Besong GE, Bostock JM, Stubbings W, Chopra I, Roper DI, Lloyd AJ, Fishwick CW, Johnson AP. Besong GE, et al. Among authors: chopra i. Angew Chem Int Ed Engl. 2005 Oct 7;44(39):6403-6. doi: 10.1002/anie.200501662. Angew Chem Int Ed Engl. 2005. PMID: 16158456 No abstract available.
Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.
Derouaux A, Turk S, Olrichs NK, Gobec S, Breukink E, Amoroso A, Offant J, Bostock J, Mariner K, Chopra I, Vernet T, Zervosen A, Joris B, Frère JM, Nguyen-Distèche M, Terrak M. Derouaux A, et al. Among authors: chopra i. Biochem Pharmacol. 2011 May 1;81(9):1098-105. doi: 10.1016/j.bcp.2011.02.008. Epub 2011 Feb 26. Biochem Pharmacol. 2011. PMID: 21356201
521 results