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Manipulation of catechol-O-methyl-transferase (COMT) activity to influence the attenuation of substance seeking behavior, a subtype of Reward Deficiency Syndrome (RDS), is dependent upon gene polymorphisms: a hypothesis.
Blum K, Chen TJ, Meshkin B, Waite RL, Downs BW, Blum SH, Mengucci JF, Arcuri V, Braverman ER, Palomo T. Blum K, et al. Among authors: mengucci jf. Med Hypotheses. 2007;69(5):1054-60. doi: 10.1016/j.mehy.2006.12.062. Epub 2007 Apr 30. Med Hypotheses. 2007. PMID: 17467918
Plasma growth hormones, P300 event-related potential and test of variables of attention (TOVA) are important neuroendocrinological predictors of early cognitive decline in a clinical setting: evidence supported by structural equation modeling (SEM) parameter estimates.
Braverman ER, Chen TJ, Prihoda TJ, Sonntag W, Meshkin B, Downs BW, Mengucci JF, Blum SH, Notaro A, Arcuri V, Varshavskiy M, Blum K. Braverman ER, et al. Among authors: mengucci jf. Age (Dordr). 2007 Sep;29(2-3):55-67. doi: 10.1007/s11357-007-9030-3. Epub 2007 May 12. Age (Dordr). 2007. PMID: 19424831 Free PMC article.