Lin TT - Search Results

1

Highly purified CD38+ and CD38- sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin.

Pepper C, Ward R, Lin TT, Brennan P, Starczynski J, Musson M, Rowntree C, Bentley P, Mills K, Pratt G, Fegan C. Pepper C, et al. Among authors: lin tt. Leukemia. 2007 Apr;21(4):687-96. doi: 10.1038/sj.leu.2404587. Epub 2007 Feb 8. Leukemia. 2007. PMID: 17287849

2

Highly purified CD38 sub-populations show no evidence of preferential clonal evolution despite having increased proliferative activity when compared with CD38 sub-populations derived from the same chronic lymphocytic leukaemia patient.

Lin TT, Hewamana S, Ward R, Taylor H, Payne T, Pratt G, Baird D, Fegan C, Pepper C. Lin TT, et al. Br J Haematol. 2008 Aug;142(4):595-605. doi: 10.1111/j.1365-2141.2008.07236.x. Epub 2008 May 22. Br J Haematol. 2008. PMID: 18503580 Free article.

3

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

Pepper C, Lin TT, Pratt G, Hewamana S, Brennan P, Hiller L, Hills R, Ward R, Starczynski J, Austen B, Hooper L, Stankovic T, Fegan C. Pepper C, et al. Among authors: lin tt. Blood. 2008 Nov 1;112(9):3807-17. doi: 10.1182/blood-2008-05-157131. Epub 2008 Jul 3. Blood. 2008. PMID: 18599795 Free article.

4

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

Hewamana S, Lin TT, Rowntree C, Karunanithi K, Pratt G, Hills R, Fegan C, Brennan P, Pepper C. Hewamana S, et al. Among authors: lin tt. J Clin Oncol. 2009 Feb 10;27(5):763-9. doi: 10.1200/JCO.2008.19.1114. Epub 2009 Jan 5. J Clin Oncol. 2009. PMID: 19124804

5

Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38.

Pearce L, Morgan L, Lin TT, Hewamana S, Matthews RJ, Deaglio S, Rowntree C, Fegan C, Pepper C, Brennan P. Pearce L, et al. Among authors: lin tt. Haematologica. 2010 Mar;95(3):514-7. doi: 10.3324/haematol.2009.014381. Haematologica. 2010. PMID: 20207849 Free PMC article.

6

CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38- counter-parts.

Pepper C, Brennan P, Alghazal S, Ward R, Pratt G, Starczynski J, Lin T, Rowntree C, Fegan C. Pepper C, et al. Leukemia. 2006 Apr;20(4):743-4. doi: 10.1038/sj.leu.2404133. Leukemia. 2006. PMID: 16452999 No abstract available.

7

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target.

Hewamana S, Alghazal S, Lin TT, Clement M, Jenkins C, Guzman ML, Jordan CT, Neelakantan S, Crooks PA, Burnett AK, Pratt G, Fegan C, Rowntree C, Brennan P, Pepper C. Hewamana S, et al. Among authors: lin tt. Blood. 2008 May 1;111(9):4681-9. doi: 10.1182/blood-2007-11-125278. Epub 2008 Jan 28. Blood. 2008. PMID: 18227347 Free article.

8

The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine.

Hewamana S, Lin TT, Jenkins C, Burnett AK, Jordan CT, Fegan C, Brennan P, Rowntree C, Pepper C. Hewamana S, et al. Among authors: lin tt. Clin Cancer Res. 2008 Dec 15;14(24):8102-11. doi: 10.1158/1078-0432.CCR-08-1673. Clin Cancer Res. 2008. PMID: 19088025

9

Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis.

Lin TT, Letsolo BT, Jones RE, Rowson J, Pratt G, Hewamana S, Fegan C, Pepper C, Baird DM. Lin TT, et al. Blood. 2010 Sep 16;116(11):1899-907. doi: 10.1182/blood-2010-02-272104. Epub 2010 Jun 10. Blood. 2010. PMID: 20538793 Free article.

10

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL.

Majid A, Lin TT, Best G, Fishlock K, Hewamana S, Pratt G, Yallop D, Buggins AG, Wagner S, Kennedy BJ, Miall F, Hills R, Devereux S, Oscier DG, Dyer MJ, Fegan C, Pepper C. Majid A, et al. Among authors: lin tt. Leuk Res. 2011 Jun;35(6):750-6. doi: 10.1016/j.leukres.2010.10.022. Epub 2010 Nov 18. Leuk Res. 2011. PMID: 21093051

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