Krecmerová M - Search Results

1

Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.

Krecmerová M, Holý A, Pískala A, Masojídková M, Andrei G, Naesens L, Neyts J, Balzarini J, De Clercq E, Snoeck R. Krecmerová M, et al. J Med Chem. 2007 Mar 8;50(5):1069-77. doi: 10.1021/jm061281+. Epub 2007 Feb 14. J Med Chem. 2007. PMID: 17298047

2

Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.

Krecmerová M, Holý A, Pohl R, Masojídková M, Andrei G, Naesens L, Neyts J, Balzarini J, De Clercq E, Snoeck R. Krecmerová M, et al. J Med Chem. 2007 Nov 15;50(23):5765-72. doi: 10.1021/jm0707166. Epub 2007 Oct 19. J Med Chem. 2007. PMID: 17948980

3

Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy.

Dracínský M, Krecmerová M, Holý A. Dracínský M, et al. Among authors: krecmerova m. Bioorg Med Chem. 2008 Jul 15;16(14):6778-82. doi: 10.1016/j.bmc.2008.05.058. Epub 2008 Jun 12. Bioorg Med Chem. 2008. PMID: 18554916

4

Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position.

Krecmerová M, Masojídková M, Holý A. Krecmerová M, et al. Bioorg Med Chem. 2010 Jan 1;18(1):387-95. doi: 10.1016/j.bmc.2009.10.044. Epub 2009 Oct 29. Bioorg Med Chem. 2010. PMID: 19914075

5

Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.

Krecmerová M, Holý A, Andrei G, Pomeisl K, Tichý T, Brehová P, Masojídková M, Dracínský M, Pohl R, Laflamme G, Naesens L, Hui H, Cihlar T, Neyts J, De Clercq E, Balzarini J, Snoeck R. Krecmerová M, et al. J Med Chem. 2010 Oct 14;53(19):6825-37. doi: 10.1021/jm901828c. J Med Chem. 2010. PMID: 20809641

6

New prodrugs of Adefovir and Cidofovir.

Tichý T, Andrei G, Dračínský M, Holý A, Balzarini J, Snoeck R, Krečmerová M. Tichý T, et al. Among authors: krecmerova m. Bioorg Med Chem. 2011 Jun 1;19(11):3527-39. doi: 10.1016/j.bmc.2011.04.016. Epub 2011 Apr 22. Bioorg Med Chem. 2011. PMID: 21565516 Free PMC article.

7

Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents.

Krečmerová M, Dračínský M, Hocková D, Holý A, Keough DT, Guddat LW. Krečmerová M, et al. Bioorg Med Chem. 2012 Feb 1;20(3):1222-30. doi: 10.1016/j.bmc.2011.12.034. Epub 2011 Dec 30. Bioorg Med Chem. 2012. PMID: 22249123

8

Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety.

Tichý T, Andrei G, Snoeck R, Balzarini J, Dračínský M, Krečmerová M. Tichý T, et al. Among authors: krecmerova m. Eur J Med Chem. 2012 Sep;55:307-14. doi: 10.1016/j.ejmech.2012.07.027. Epub 2012 Jul 24. Eur J Med Chem. 2012. PMID: 22858222 Free PMC article.

9

9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro.

Krečmerová M, Jansa P, Dračínský M, Sázelová P, Kašička V, Neyts J, Auwerx J, Kiss E, Goris N, Stepan G, Janeba Z. Krečmerová M, et al. Bioorg Med Chem. 2013 Mar 1;21(5):1199-208. doi: 10.1016/j.bmc.2012.12.044. Epub 2013 Jan 9. Bioorg Med Chem. 2013. PMID: 23375089 Free PMC article.

10

N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity.

Krečmerová M, Pohl R, Masojídková M, Balzarini J, Snoeck R, Andrei G. Krečmerová M, et al. Bioorg Med Chem. 2014 May 15;22(10):2896-906. doi: 10.1016/j.bmc.2014.03.031. Epub 2014 Mar 26. Bioorg Med Chem. 2014. PMID: 24731540

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