Rosato RR - Search Results

1

Mechanism and functional role of XIAP and Mcl-1 down-regulation in flavopiridol/vorinostat antileukemic interactions.

Rosato RR, Almenara JA, Kolla SS, Maggio SC, Coe S, Giménez MS, Dent P, Grant S. Rosato RR, et al. Mol Cancer Ther. 2007 Feb;6(2):692-702. doi: 10.1158/1535-7163.MCT-06-0562. Mol Cancer Ther. 2007. PMID: 17308065

2

LBH-589 (panobinostat) potentiates fludarabine anti-leukemic activity through a JNK- and XIAP-dependent mechanism.

Rosato R, Hock S, Dent P, Dai Y, Grant S. Rosato R, et al. Leuk Res. 2012 Apr;36(4):491-8. doi: 10.1016/j.leukres.2011.10.020. Epub 2011 Nov 8. Leuk Res. 2012. PMID: 22074700 Free PMC article.

3

Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway.

Yaseen A, Chen S, Hock S, Rosato R, Dent P, Dai Y, Grant S. Yaseen A, et al. Mol Pharmacol. 2012 Dec;82(6):1030-41. doi: 10.1124/mol.112.079624. Epub 2012 Aug 24. Mol Pharmacol. 2012. PMID: 22923501 Free PMC article.

4

The cyclin-dependent kinase inhibitor flavopiridol disrupts sodium butyrate-induced p21WAF1/CIP1 expression and maturation while reciprocally potentiating apoptosis in human leukemia cells.

Rosato RR, Almenara JA, Cartee L, Betts V, Chellappan SP, Grant S. Rosato RR, et al. Mol Cancer Ther. 2002 Feb;1(4):253-66. Mol Cancer Ther. 2002. PMID: 12467221

5

Histone deacetylase inhibitors in cancer therapy.

Rosato RR, Grant S. Rosato RR, et al. Cancer Biol Ther. 2003 Jan-Feb;2(1):30-7. doi: 10.4161/cbt.190. Cancer Biol Ther. 2003. PMID: 12673114 Free article. Review.

6

The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.

Rosato RR, Almenara JA, Grant S. Rosato RR, et al. Cancer Res. 2003 Jul 1;63(13):3637-45. Cancer Res. 2003. PMID: 12839953

7

Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells.

Rosato RR, Almenara JA, Dai Y, Grant S. Rosato RR, et al. Mol Cancer Ther. 2003 Dec;2(12):1273-84. Mol Cancer Ther. 2003. PMID: 14707268

8

Evidence of a functional role for p21WAF1/CIP1 down-regulation in synergistic antileukemic interactions between the histone deacetylase inhibitor sodium butyrate and flavopiridol.

Rosato RR, Almenara JA, Yu C, Grant S. Rosato RR, et al. Mol Pharmacol. 2004 Mar;65(3):571-81. doi: 10.1124/mol.65.3.571. Mol Pharmacol. 2004. PMID: 14978235

9

The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.

Maggio SC, Rosato RR, Kramer LB, Dai Y, Rahmani M, Paik DS, Czarnik AC, Payne SG, Spiegel S, Grant S. Maggio SC, et al. Among authors: rosato rr. Cancer Res. 2004 Apr 1;64(7):2590-600. doi: 10.1158/0008-5472.can-03-2631. Cancer Res. 2004. PMID: 15059916

10

The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide.

Rosato RR, Maggio SC, Almenara JA, Payne SG, Atadja P, Spiegel S, Dent P, Grant S. Rosato RR, et al. Mol Pharmacol. 2006 Jan;69(1):216-25. doi: 10.1124/mol.105.017145. Epub 2005 Sep 27. Mol Pharmacol. 2006. Retraction in: Mol Pharmacol. 2019 Apr;95(4):336. doi: 10.1124/mol.105.017145retraction. PMID: 16189296 Retracted.

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