Kehne JH - Search Results

1

Effects of the serotonin releasers 3,4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle reflexes in rats.

Kehne JH, McCloskey TC, Taylor VL, Black CK, Fadayel GM, Schmidt CJ. Kehne JH, et al. J Pharmacol Exp Ther. 1992 Jan;260(1):78-89. J Pharmacol Exp Ther. 1992. PMID: 1731054

2

Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies.

Sorensen SM, Kehne JH, Fadayel GM, Humphreys TM, Ketteler HJ, Sullivan CK, Taylor VL, Schmidt CJ. Sorensen SM, et al. Among authors: kehne jh. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91. J Pharmacol Exp Ther. 1993. PMID: 8102646

3

5-HT modulation of auditory and visual sensorimotor gating: I. Effects of 5-HT releasers on sound and light prepulse inhibition in Wistar rats.

Kehne JH, Padich RA, McCloskey TC, Taylor VL, Schmidt CJ. Kehne JH, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):95-106. doi: 10.1007/BF02245609. Psychopharmacology (Berl). 1996. PMID: 8935804

4

NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations.

Kehne JH, McCloskey TC, Baron BM, Chi EM, Harrison BL, Whitten JP, Palfreyman MG. Kehne JH, et al. Eur J Pharmacol. 1991 Feb 14;193(3):283-92. doi: 10.1016/0014-2999(91)90141-c. Eur J Pharmacol. 1991. PMID: 1675993

5

Neurotoxicity of MDMA: neurochemical effects.

Schmidt CJ, Kehne JH. Schmidt CJ, et al. Among authors: kehne jh. Ann N Y Acad Sci. 1990;600:665-80; discussion 680-1. doi: 10.1111/j.1749-6632.1990.tb16917.x. Ann N Y Acad Sci. 1990. PMID: 1979217 Review. No abstract available.

6

Contribution of serotonin neurotoxins to understanding psychiatric disorders: the role of 5-HT2 receptors in schizophrenia and antipsychotic activity.

Schmidt CJ, Kehne JH, Carr AA, Fadayel GM, Humphreys TM, Kettler HJ, McCloskey TC, Padich RA, Taylor VL, Sorensen SM. Schmidt CJ, et al. Among authors: kehne jh. Int Clin Psychopharmacol. 1993 Nov;8 Suppl 2:25-32. Int Clin Psychopharmacol. 1993. PMID: 7911139 Review. No abstract available.

7

MDL 100,458 and MDL 102,288: two potent and selective glycine receptor antagonists with different functional profiles.

Kehne JH, Baron BM, Harrison BL, McCloskey TC, Palfreyman MG, Poirot M, Salituro FG, Siegel BW, Slone AL, Van Giersbergen PL, et al. Kehne JH, et al. Eur J Pharmacol. 1995 Sep 15;284(1-2):109-18. doi: 10.1016/0014-2999(95)00375-u. Eur J Pharmacol. 1995. PMID: 8549613

8

Mixed D2/5-HT2A antagonism of amphetamine-induced facilitation of brain stimulation reward.

Frank RA, Tsibulsky V, Grocki S, Dashevsky B, Kehne JH, Schmidt CJ, Sorensen SM. Frank RA, et al. Among authors: kehne jh. Pharmacol Biochem Behav. 1995 Dec;52(4):799-804. doi: 10.1016/0091-3057(95)00184-x. Pharmacol Biochem Behav. 1995. PMID: 8587922

9

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile.

Kehne JH, Baron BM, Carr AA, Chaney SF, Elands J, Feldman DJ, Frank RA, van Giersbergen PL, McCloskey TC, Johnson MP, McCarty DR, Poirot M, Senyah Y, Siegel BW, Widmaier C. Kehne JH, et al. J Pharmacol Exp Ther. 1996 May;277(2):968-81. J Pharmacol Exp Ther. 1996. PMID: 8627580

10

Effects of the selective 5-HT2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats.

Kehne JH, Ketteler HJ, McCloskey TC, Sullivan CK, Dudley MW, Schmidt CJ. Kehne JH, et al. Neuropsychopharmacology. 1996 Aug;15(2):116-24. doi: 10.1016/0893-133X(95)00160-F. Neuropsychopharmacology. 1996. PMID: 8840347

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