Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution.
De Jong JJ, De Ronde A, Keulen W, Tersmette M, Goudsmit J.
De Jong JJ, et al. Among authors: tersmette m.
J Virol. 1992 Nov;66(11):6777-80. doi: 10.1128/JVI.66.11.6777-6780.1992.
J Virol. 1992.
PMID: 1404617
Free PMC article.
This study proves that introduction of a positively charged amino acid at position 306 or 320, previously shown to be strongly associated with the SI phenotype in field isolates (R.A.M. Fouchier, M. Groenink, N.A. Kootstra, M. Tersmette, H.G. Huisman, …
This study proves that introduction of a positively charged amino acid at position 306 or 320, previously shown to be strongly associated wi …