Sesnie JC - Search Results

1

New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8-fluoro group with reduced phototoxic risk.

Sanchez JP, Bridges AJ, Bucsh R, Domagala JM, Gogliotti RD, Hagen SE, Heifetz CL, Joannides ET, Sesnie JC, Shapiro MA, et al. Sanchez JP, et al. Among authors: sesnie jc. J Med Chem. 1992 Jan 24;35(2):361-7. doi: 10.1021/jm00080a023. J Med Chem. 1992. PMID: 1732554

2

Quinolone antibacterials: preparation and activity of bridged bicyclic analogues of the C7-piperazine.

Kiely JS, Hutt MP, Culbertson TP, Bucsh RA, Worth DF, Lesheski LE, Gogliotti RD, Sesnie JC, Solomon M, Mich TF. Kiely JS, et al. Among authors: sesnie jc. J Med Chem. 1991 Feb;34(2):656-63. doi: 10.1021/jm00106a029. J Med Chem. 1991. PMID: 1995890

3

Comparative chemotherapeutic activity of new fluorinated 4-quinolones and standard agents against a variety of bacteria in a mouse infection model.

Sesnie JC, Fritsch PW, Griffin TJ, Heifetz CL, Leopold ET, Malta TE, Shapiro MA, Vincent PW. Sesnie JC, et al. J Antimicrob Chemother. 1989 May;23(5):729-36. doi: 10.1093/jac/23.5.729. J Antimicrob Chemother. 1989. PMID: 2759922

4

Synthesis and antimicrobial evaluation of a series of 7-[3-amino (or aminomethyl)-4-aryl (or cyclopropyl)-1-pyrrolidinyl]-4-quinolone- and -1,8-naphthyridone-3-carboxylic acids.

Bucsh RA, Domagala JM, Laborde E, Sesnie JC. Bucsh RA, et al. Among authors: sesnie jc. J Med Chem. 1993 Dec 24;36(26):4139-51. doi: 10.1021/jm00078a002. J Med Chem. 1993. PMID: 8277495

5

In vivo therapeutic efficacies of PD 138312 and PD 140248, two novel fluoronaphthyridines with outstanding gram-positive potency.

Shapiro MA, Dever JA, Joannides ET, Sesnie JC, Vanderroest SR. Shapiro MA, et al. Among authors: sesnie jc. Antimicrob Agents Chemother. 1995 Oct;39(10):2183-6. doi: 10.1128/AAC.39.10.2183. Antimicrob Agents Chemother. 1995. PMID: 8619563 Free PMC article.

6

A novel rapid throughput phototolerance screen in mice.

Shapiro MA, Sesnie JC, Joannides ET, Malta TE, Dever JA, Heifetz CL. Shapiro MA, et al. Among authors: sesnie jc. J Pharmacol Toxicol Methods. 1996 Dec;36(4):185-7. doi: 10.1016/s1056-8719(96)00109-8. J Pharmacol Toxicol Methods. 1996. PMID: 9040108

7

Enoxacin: in-vitro and animal evaluation as a parenteral and oral agent against hospital bacterial isolates.

Heifetz CL, Bien PA, Cohen MA, Dombrowski ME, Griffin TJ, Malta TE, Sesnie JC, Shapiro MA, Wold SA. Heifetz CL, et al. Among authors: sesnie jc. J Antimicrob Chemother. 1988 Feb;21 Suppl B:29-42. doi: 10.1093/jac/21.suppl_b.29. J Antimicrob Chemother. 1988. PMID: 3129392

8

In vitro evaluation of cefdinir (FK482), a new oral cephalosporin with enhanced antistaphylococcal activity and beta-lactamase stability.

Cohen MA, Joannides ET, Roland GE, Meservey MA, Huband MD, Shapiro MA, Sesnie JC, Heifetz CL. Cohen MA, et al. Among authors: sesnie jc. Diagn Microbiol Infect Dis. 1994 Jan;18(1):31-9. doi: 10.1016/0732-8893(94)90131-7. Diagn Microbiol Infect Dis. 1994. PMID: 8026155

9

Comparative therapeutic efficacy of clinafloxacin in leucopenic mice.

Shapiro MA, Dever JA, Sesnie JC, VanderRoest SR. Shapiro MA, et al. Among authors: sesnie jc. J Antimicrob Chemother. 1997 Feb;39(2):273-6. doi: 10.1093/jac/39.2.273. J Antimicrob Chemother. 1997. PMID: 9069553

10

Comparative therapeutic efficacy of clinafloxacin in a Pseudomonas aeruginosa mouse renal abscess model.

Shapiro MA, Sesnie JC, Desaty TM, Griffin TJ, Heifetz CL. Shapiro MA, et al. Among authors: sesnie jc. J Antimicrob Chemother. 1998 Mar;41(3):403-5. doi: 10.1093/jac/41.3.403. J Antimicrob Chemother. 1998. PMID: 9578169

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