Kujoth GC - Search Results

1

Mitochondrial point mutations do not limit the natural lifespan of mice.

Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA. Vermulst M, et al. Among authors: kujoth gc. Nat Genet. 2007 Apr;39(4):540-3. doi: 10.1038/ng1988. Epub 2007 Mar 4. Nat Genet. 2007. PMID: 17334366

2

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.

Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA. Vermulst M, et al. Among authors: kujoth gc. Nat Genet. 2008 Apr;40(4):392-4. doi: 10.1038/ng.95. Epub 2008 Mar 2. Nat Genet. 2008. PMID: 18311139

3

Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity.

Hansen AB, Griner NB, Anderson JP, Kujoth GC, Prolla TA, Loeb LA, Glick E. Hansen AB, et al. Among authors: kujoth gc. DNA Repair (Amst). 2006 Jan 5;5(1):71-9. doi: 10.1016/j.dnarep.2005.07.009. Epub 2005 Sep 13. DNA Repair (Amst). 2006. PMID: 16165404

4

Mitochondrial DNA mutations and apoptosis in mammalian aging.

Kujoth GC, Leeuwenburgh C, Prolla TA. Kujoth GC, et al. Cancer Res. 2006 Aug 1;66(15):7386-9. doi: 10.1158/0008-5472.CAN-05-4670. Cancer Res. 2006. PMID: 16885331 Review.

5

The role of mitochondrial DNA mutations in mammalian aging.

Kujoth GC, Bradshaw PC, Haroon S, Prolla TA. Kujoth GC, et al. PLoS Genet. 2007 Feb 23;3(2):e24. doi: 10.1371/journal.pgen.0030024. PLoS Genet. 2007. PMID: 17319745 Free PMC article. Review.

6

Evolving insight into the role of mitochondrial DNA mutations in aging.

Kujoth GC, Prolla TA. Kujoth GC, et al. Exp Gerontol. 2008 Jan;43(1):20-3. doi: 10.1016/j.exger.2007.09.010. Epub 2007 Oct 5. Exp Gerontol. 2008. PMID: 18054193 Review.

7

Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.

Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N. Fox R, et al. Among authors: kujoth gc. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8779-84. doi: 10.1073/pnas.1106344108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555558 Free PMC article.

8

Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption.

Fox RG, Magness S, Kujoth GC, Prolla TA, Maeda N. Fox RG, et al. Among authors: kujoth gc. Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G914-24. doi: 10.1152/ajpgi.00402.2011. Epub 2012 Feb 16. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22345551 Free PMC article.

9

Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice.

Dai Y, Clark J, Zheng K, Kujoth GC, Prolla TA, Simon DK. Dai Y, et al. Among authors: kujoth gc. Neurotoxicol Teratol. 2014 Nov-Dec;46:62-7. doi: 10.1016/j.ntt.2014.10.004. Neurotoxicol Teratol. 2014. PMID: 25450660 Free PMC article.

10

Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice.

Someya S, Kujoth GC, Kim MJ, Hacker TA, Vermulst M, Weindruch R, Prolla TA. Someya S, et al. Among authors: kujoth gc. PLoS One. 2017 Feb 3;12(2):e0171159. doi: 10.1371/journal.pone.0171159. eCollection 2017. PLoS One. 2017. PMID: 28158260 Free PMC article.

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