Frydenvang K - Search Results

1

Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid.

Conti P, Caligiuri A, Pinto A, Roda G, Tamborini L, Nielsen B, Madsen U, Frydenvang K, Colombo A, De Micheli C. Conti P, et al. Among authors: frydenvang k. Eur J Med Chem. 2007 Aug;42(8):1059-68. doi: 10.1016/j.ejmech.2007.01.013. Epub 2007 Jan 27. Eur J Med Chem. 2007. PMID: 17346858

2

Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538.

Bay Y, Cabello FJM, Koens CC, Frantsen SM, Pickering DS, Frydenvang K, Francotte P, Pirotte B, Kristensen AS, Bowie D, Kastrup JS. Bay Y, et al. Among authors: frydenvang k. J Struct Biol. 2024 Sep;216(3):108113. doi: 10.1016/j.jsb.2024.108113. Epub 2024 Jul 28. J Struct Biol. 2024. PMID: 39079583 Free article.

3

The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2.

Bay Y, Egeberg Jeppesen M, Frydenvang K, Francotte P, Pirotte B, Pickering DS, Kristensen AS, Kastrup JS. Bay Y, et al. Among authors: frydenvang k. FEBS Lett. 2024 Apr;598(7):743-757. doi: 10.1002/1873-3468.14824. Epub 2024 Feb 18. FEBS Lett. 2024. PMID: 38369668

4

Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.

Bay Y, Venskutonytė R, Frantsen SM, Thorsen TS, Musgaard M, Frydenvang K, Francotte P, Pirotte B, Biggin PC, Kristensen AS, Boesen T, Pickering DS, Gajhede M, Kastrup JS. Bay Y, et al. Among authors: frydenvang k. FEBS J. 2024 Apr;291(7):1506-1529. doi: 10.1111/febs.17046. Epub 2024 Feb 23. FEBS J. 2024. PMID: 38145505

5

Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands.

Johansen TN, Frydenvang K, Ebert B, Krogsgaard-Larsen P, Madsen U. Johansen TN, et al. Among authors: frydenvang k. J Med Chem. 1994 Sep 30;37(20):3252-62. doi: 10.1021/jm00046a009. J Med Chem. 1994. PMID: 7523673

6

N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.

Madsen U, Frydenvang K, Ebert B, Johansen TN, Brehm L, Krogsgaard-Larsen P. Madsen U, et al. Among authors: frydenvang k. J Med Chem. 1996 Jan 5;39(1):183-90. doi: 10.1021/jm950393q. J Med Chem. 1996. PMID: 8568805

7

Excitatory amino acid receptor antagonists: resolution, absolute stereochemistry, and pharmacology of (S)- and (R)-2-amino-2-(5-tert-butyl-3-hydroxyisoxazol-4-yl)acetic acid (ATAA).

Johansen TN, Frydenvang K, Ebert B, Madsen U, Krogsgaard-Larsen P. Johansen TN, et al. Among authors: frydenvang k. Chirality. 1997;9(5-6):529-36. doi: 10.1002/(SICI)1520-636X(1997)9:5/6<529::AID-CHIR20>3.0.CO;2-P. Chirality. 1997. PMID: 9329180

8

Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist.

Stensbøl TB, Jensen HS, Nielsen B, Johansen TN, Egebjerg J, Frydenvang K, Krogsgaard-Larsen P. Stensbøl TB, et al. Among authors: frydenvang k. Eur J Pharmacol. 2001 Jan 12;411(3):245-53. doi: 10.1016/s0014-2999(00)00916-x. Eur J Pharmacol. 2001. PMID: 11164381

9

Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors.

Madsen U, Bräuner-Osborne H, Frydenvang K, Hvene L, Johansen TN, Nielsen B, Sánchez C, Stensbøl TB, Bischoff F, Krogsgaard-Larsen P. Madsen U, et al. Among authors: frydenvang k. J Med Chem. 2001 Mar 29;44(7):1051-9. doi: 10.1021/jm000441t. J Med Chem. 2001. PMID: 11297452

10

Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol.

Bunch L, Norrby PO, Frydenvang K, Krogsgaard-Larsen P, Madsen U. Bunch L, et al. Among authors: frydenvang k. Org Lett. 2001 Feb 8;3(3):433-5. doi: 10.1021/ol0069397. Org Lett. 2001. PMID: 11428032

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