Leurs R - Search Results

1

The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons.

Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z. Dai H, et al. Among authors: leurs r. Eur J Pharmacol. 2007 Jun 1;563(1-3):117-23. doi: 10.1016/j.ejphar.2007.01.069. Epub 2007 Feb 8. Eur J Pharmacol. 2007. PMID: 17350613

2

Desensitization of histamine H1 receptor-mediated cyclic GMP production in guinea-pig lung.

Leurs R, Brozius MM, Jansen W, Bast A, Timmerman H. Leurs R, et al. Eur J Pharmacol. 1992 Feb 13;225(2):137-41. doi: 10.1016/0922-4106(92)90093-b. Eur J Pharmacol. 1992. PMID: 1312939

3

The histamine H3-receptor: a target for developing new drugs.

Leurs R, Timmerman H. Leurs R, et al. Prog Drug Res. 1992;39:127-65. doi: 10.1007/978-3-0348-7144-0_4. Prog Drug Res. 1992. PMID: 1335582 Review. No abstract available.

4

Short-term desensitization of the histamine H1 receptor in human HeLa cells: involvement of protein kinase C dependent and independent pathways.

Smit MJ, Bloemers SM, Leurs R, Tertoolen LG, Bast A, de Laat SW, Timmerman H. Smit MJ, et al. Among authors: leurs r. Br J Pharmacol. 1992 Oct;107(2):448-55. doi: 10.1111/j.1476-5381.1992.tb12766.x. Br J Pharmacol. 1992. PMID: 1422591 Free PMC article.

5

Effects of histamine H1-, H2- and H3-receptor selective drugs on the mechanical activity of guinea-pig small and large intestine.

Leurs R, Brozius MM, Smit MJ, Bast A, Timmerman H. Leurs R, et al. Br J Pharmacol. 1991 Jan;102(1):179-85. doi: 10.1111/j.1476-5381.1991.tb12150.x. Br J Pharmacol. 1991. PMID: 1646056 Free PMC article.

6

Is protein kinase C involved in histamine H1-receptor desensitization?

Leurs R, Smit MJ, Brozius MM, Jansen W, Bast A, Timmerman H. Leurs R, et al. Agents Actions Suppl. 1991;33:393-402. doi: 10.1007/978-3-0348-7309-3_29. Agents Actions Suppl. 1991. PMID: 1647131

7

Histamine H1-receptor-mediated cyclic GMP production in guinea-pig lung tissue is an L-arginine-dependent process.

Leurs R, Brozius MM, Jansen W, Bast A, Timmerman H. Leurs R, et al. Biochem Pharmacol. 1991 Jul 5;42(2):271-7. doi: 10.1016/0006-2952(91)90713-f. Biochem Pharmacol. 1991. PMID: 1650206

8

Homologous histamine H1 receptor desensitization results in reduction of H1 receptor agonist efficacy.

Leurs R, Smit MJ, Bast A, Timmerman H. Leurs R, et al. Eur J Pharmacol. 1991 Apr 24;196(3):319-22. doi: 10.1016/0014-2999(91)90446-w. Eur J Pharmacol. 1991. PMID: 1654256

9

Fluoride is a contractile agent of guinea pig airway smooth muscle.

Leurs R, Bast A, Timmerman H. Leurs R, et al. Gen Pharmacol. 1991;22(4):631-6. doi: 10.1016/0306-3623(91)90068-h. Gen Pharmacol. 1991. PMID: 1657687

10

Desensitization of guinea-pig parenchymal lung strips after prolonged histamine H1-receptor stimulation.

Leurs R, Go JN, Bast A, Timmerman H. Leurs R, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:265-76. Arch Int Pharmacodyn Ther. 1990. PMID: 1978644

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