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A major non-HLA locus in celiac disease maps to chromosome 19.
Van Belzen MJ, Meijer JW, Sandkuijl LA, Bardoel AF, Mulder CJ, Pearson PL, Houwen RH, Wijmenga C. Van Belzen MJ, et al. Among authors: wijmenga c. Gastroenterology. 2003 Oct;125(4):1032-41. doi: 10.1016/s0016-5085(03)01205-8. Gastroenterology. 2003. PMID: 14517787
Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect.
Monsuur AJ, de Bakker PI, Alizadeh BZ, Zhernakova A, Bevova MR, Strengman E, Franke L, van't Slot R, van Belzen MJ, Lavrijsen IC, Diosdado B, Daly MJ, Mulder CJ, Mearin ML, Meijer JW, Meijer GA, van Oort E, Wapenaar MC, Koeleman BP, Wijmenga C. Monsuur AJ, et al. Among authors: wijmenga c. Nat Genet. 2005 Dec;37(12):1341-4. doi: 10.1038/ng1680. Epub 2005 Nov 13. Nat Genet. 2005. PMID: 16282976
Identification of TUB as a novel candidate gene influencing body weight in humans.
Shiri-Sverdlov R, Custers A, van Vliet-Ostaptchouk JV, van Gorp PJ, Lindsey PJ, van Tilburg JH, Zhernakova S, Feskens EJ, van der A DL, Dollé ME, van Haeften TW, Koeleman BP, Hofker MH, Wijmenga C. Shiri-Sverdlov R, et al. Among authors: wijmenga c. Diabetes. 2006 Feb;55(2):385-9. doi: 10.2337/diabetes.55.02.06.db05-0997. Diabetes. 2006. PMID: 16443771 Free article.
A strategy to search for common obesity and type 2 diabetes genes.
Elbers CC, Onland-Moret NC, Franke L, Niehoff AG, van der Schouw YT, Wijmenga C. Elbers CC, et al. Among authors: wijmenga c. Trends Endocrinol Metab. 2007 Jan-Feb;18(1):19-26. doi: 10.1016/j.tem.2006.11.003. Epub 2006 Nov 28. Trends Endocrinol Metab. 2007. PMID: 17126559 Review.
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes GK, Feighery C, Jewell D, Kelleher D, Kumar P, Travis S, Walters JR, Sanders DS, Howdle P, Swift J, Playford RJ, McLaren WM, Mearin ML, Mulder CJ, McManus R, McGinnis R, Cardon LR, Deloukas P, Wijmenga C. van Heel DA, et al. Among authors: wijmenga c. Nat Genet. 2007 Jul;39(7):827-9. doi: 10.1038/ng2058. Epub 2007 Jun 10. Nat Genet. 2007. PMID: 17558408 Free PMC article.
713 results