Wright GD - Search Results

1

Role of homoserine transacetylase as a new target for antifungal agents.

Nazi I, Scott A, Sham A, Rossi L, Williamson PR, Kronstad JW, Wright GD. Nazi I, et al. Among authors: wright gd. Antimicrob Agents Chemother. 2007 May;51(5):1731-6. doi: 10.1128/AAC.01400-06. Epub 2007 Mar 12. Antimicrob Agents Chemother. 2007. PMID: 17353245 Free PMC article.

2

Recognition of aminoglycoside antibiotics by enterococcal-staphylococcal aminoglycoside 3'-phosphotransferase type IIIa: role of substrate amino groups.

McKay GA, Roestamadji J, Mobashery S, Wright GD. McKay GA, et al. Among authors: wright gd. Antimicrob Agents Chemother. 1996 Nov;40(11):2648-50. doi: 10.1128/AAC.40.11.2648. Antimicrob Agents Chemother. 1996. PMID: 8913482 Free PMC article.

3

Overexpression and characterization of the chromosomal aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium.

Wright GD, Ladak P. Wright GD, et al. Antimicrob Agents Chemother. 1997 May;41(5):956-60. doi: 10.1128/AAC.41.5.956. Antimicrob Agents Chemother. 1997. PMID: 9145851 Free PMC article.

4

Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms.

Marshall CG, Lessard IA, Park I, Wright GD. Marshall CG, et al. Among authors: wright gd. Antimicrob Agents Chemother. 1998 Sep;42(9):2215-20. doi: 10.1128/AAC.42.9.2215. Antimicrob Agents Chemother. 1998. PMID: 9736537 Free PMC article.

5

Characterization of yeast homoserine dehydrogenase, an antifungal target: the invariant histidine 309 is important for enzyme integrity.

Jacques SL, Nieman C, Bareich D, Broadhead G, Kinach R, Honek JF, Wright GD. Jacques SL, et al. Among authors: wright gd. Biochim Biophys Acta. 2001 Jan 12;1544(1-2):28-41. doi: 10.1016/s0167-4838(00)00203-x. Biochim Biophys Acta. 2001. PMID: 11341914

6

Simultaneous in vitro assay of the first four enzymes in the fungal aspartate pathway identifies a new class of aspartate kinase inhibitor.

Bareich DC, Nazi I, Wright GD. Bareich DC, et al. Among authors: wright gd. Chem Biol. 2003 Oct;10(10):967-73. doi: 10.1016/j.chembiol.2003.09.016. Chem Biol. 2003. PMID: 14583263 No abstract available.

7

Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase.

Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Jacques SL, et al. Among authors: wright gd. Chem Biol. 2003 Oct;10(10):989-95. doi: 10.1016/j.chembiol.2003.09.015. Chem Biol. 2003. PMID: 14583265

8

One-pot chemoenzymatic preparation of coenzyme A analogues.

Nazi I, Koteva KP, Wright GD. Nazi I, et al. Among authors: wright gd. Anal Biochem. 2004 Jan 1;324(1):100-5. doi: 10.1016/j.ab.2003.09.005. Anal Biochem. 2004. PMID: 14654051

9

Small molecule functional discrimination of the kinases required for the microbial synthesis of threonine and isoleucine.

Bareich D, Koteva K, Nazi I, Wright GD. Bareich D, et al. Among authors: wright gd. Bioorg Med Chem. 2004 Feb 15;12(4):807-15. doi: 10.1016/j.bmc.2003.10.042. Bioorg Med Chem. 2004. PMID: 14759741

10

New phenolic inhibitors of yeast homoserine dehydrogenase.

Ejim L, Mirza IA, Capone C, Nazi I, Jenkins S, Chee GL, Berghuis AM, Wright GD. Ejim L, et al. Among authors: wright gd. Bioorg Med Chem. 2004 Jul 15;12(14):3825-30. doi: 10.1016/j.bmc.2004.05.009. Bioorg Med Chem. 2004. PMID: 15210149

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