Krainer AR - Search Results

1

Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon.

Hua Y, Vickers TA, Baker BF, Bennett CF, Krainer AR. Hua Y, et al. Among authors: krainer ar. PLoS Biol. 2007 Apr;5(4):e73. doi: 10.1371/journal.pbio.0050073. PLoS Biol. 2007. PMID: 17355180 Free PMC article.

2

Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

Cartegni L, Krainer AR. Cartegni L, et al. Among authors: krainer ar. Nat Genet. 2002 Apr;30(4):377-84. doi: 10.1038/ng854. Epub 2002 Mar 4. Nat Genet. 2002. PMID: 11925564

3

Correction of disease-associated exon skipping by synthetic exon-specific activators.

Cartegni L, Krainer AR. Cartegni L, et al. Among authors: krainer ar. Nat Struct Biol. 2003 Feb;10(2):120-5. doi: 10.1038/nsb887. Nat Struct Biol. 2003. PMID: 12524529

4

Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.

Cartegni L, Hastings ML, Calarco JA, de Stanchina E, Krainer AR. Cartegni L, et al. Among authors: krainer ar. Am J Hum Genet. 2006 Jan;78(1):63-77. doi: 10.1086/498853. Epub 2005 Nov 16. Am J Hum Genet. 2006. PMID: 16385450 Free PMC article.

5

Antisense masking of an hnRNP A1/A2 intronic splicing silencer corrects SMN2 splicing in transgenic mice.

Hua Y, Vickers TA, Okunola HL, Bennett CF, Krainer AR. Hua Y, et al. Among authors: krainer ar. Am J Hum Genet. 2008 Apr;82(4):834-48. doi: 10.1016/j.ajhg.2008.01.014. Epub 2008 Mar 27. Am J Hum Genet. 2008. PMID: 18371932 Free PMC article.

6

Identification of synaptic targets of Drosophila pumilio.

Chen G, Li W, Zhang QS, Regulski M, Sinha N, Barditch J, Tully T, Krainer AR, Zhang MQ, Dubnau J. Chen G, et al. Among authors: krainer ar. PLoS Comput Biol. 2008 Feb 29;4(2):e1000026. doi: 10.1371/journal.pcbi.1000026. PLoS Comput Biol. 2008. PMID: 18463699 Free PMC article.

7

A positive modifier of spinal muscular atrophy in the SMN2 gene.

Prior TW, Krainer AR, Hua Y, Swoboda KJ, Snyder PC, Bridgeman SJ, Burghes AH, Kissel JT. Prior TW, et al. Among authors: krainer ar. Am J Hum Genet. 2009 Sep;85(3):408-13. doi: 10.1016/j.ajhg.2009.08.002. Epub 2009 Aug 27. Am J Hum Genet. 2009. PMID: 19716110 Free PMC article.

8

Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model.

Hua Y, Sahashi K, Hung G, Rigo F, Passini MA, Bennett CF, Krainer AR. Hua Y, et al. Among authors: krainer ar. Genes Dev. 2010 Aug 1;24(15):1634-44. doi: 10.1101/gad.1941310. Epub 2010 Jul 12. Genes Dev. 2010. PMID: 20624852 Free PMC article.

9

Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy.

Passini MA, Bu J, Richards AM, Kinnecom C, Sardi SP, Stanek LM, Hua Y, Rigo F, Matson J, Hung G, Kaye EM, Shihabuddin LS, Krainer AR, Bennett CF, Cheng SH. Passini MA, et al. Among authors: krainer ar. Sci Transl Med. 2011 Mar 2;3(72):72ra18. doi: 10.1126/scitranslmed.3001777. Sci Transl Med. 2011. PMID: 21368223 Free PMC article.

10

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model.

Hua Y, Sahashi K, Rigo F, Hung G, Horev G, Bennett CF, Krainer AR. Hua Y, et al. Among authors: krainer ar. Nature. 2011 Oct 5;478(7367):123-6. doi: 10.1038/nature10485. Nature. 2011. PMID: 21979052 Free PMC article.

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