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Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity.
Muller PA, van de Sluis B, Groot AJ, Verbeek D, Vonk WI, Maine GN, Burstein E, Wijmenga C, Vooijs M, Reits E, Klomp LW. Muller PA, et al. Among authors: groot aj. Traffic. 2009 May;10(5):514-27. doi: 10.1111/j.1600-0854.2009.00892.x. Epub 2009 Feb 11. Traffic. 2009. PMID: 19220812 Free article.
COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion.
van de Sluis B, Mao X, Zhai Y, Groot AJ, Vermeulen JF, van der Wall E, van Diest PJ, Hofker MH, Wijmenga C, Klomp LW, Cho KR, Fearon ER, Vooijs M, Burstein E. van de Sluis B, et al. Among authors: groot aj. J Clin Invest. 2010 Jun;120(6):2119-30. doi: 10.1172/JCI40583. Epub 2010 May 10. J Clin Invest. 2010. PMID: 20458141 Free PMC article.
The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2alpha.
Gort EH, van Haaften G, Verlaan I, Groot AJ, Plasterk RH, Shvarts A, Suijkerbuijk KP, van Laar T, van der Wall E, Raman V, van Diest PJ, Tijsterman M, Vooijs M. Gort EH, et al. Among authors: groot aj. Oncogene. 2008 Mar 6;27(11):1501-10. doi: 10.1038/sj.onc.1210795. Epub 2007 Sep 17. Oncogene. 2008. PMID: 17873906
Conditional inactivation of HIF-1 using intrabodies.
Groot AJ, Gort EH, van der Wall E, van Diest PJ, Vooijs M. Groot AJ, et al. Cell Oncol. 2008;30(5):397-409. doi: 10.3233/clo-2008-0442. Cell Oncol. 2008. PMID: 18791271 Free PMC article.
88 results