Gewirth D - Search Results

1

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes.

Alam SM, McAdams M, Boren D, Rak M, Scearce RM, Gao F, Camacho ZT, Gewirth D, Kelsoe G, Chen P, Haynes BF. Alam SM, et al. Among authors: gewirth d. J Immunol. 2007 Apr 1;178(7):4424-35. doi: 10.4049/jimmunol.178.7.4424. J Immunol. 2007. PMID: 17372000 Free PMC article.

2

Structural basis of androgen receptor binding to selective androgen response elements.

Shaffer PL, Jivan A, Dollins DE, Claessens F, Gewirth DT. Shaffer PL, et al. Among authors: gewirth dt. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4758-63. doi: 10.1073/pnas.0401123101. Epub 2004 Mar 22. Proc Natl Acad Sci U S A. 2004. PMID: 15037741 Free PMC article.

3

Structural basis of VDR-DNA interactions on direct repeat response elements.

Shaffer PL, Gewirth DT. Shaffer PL, et al. EMBO J. 2002 May 1;21(9):2242-52. doi: 10.1093/emboj/21.9.2242. EMBO J. 2002. PMID: 11980721 Free PMC article.

4

Vitamin D receptor-DNA interactions.

Shaffer PL, Gewirth DT. Shaffer PL, et al. Vitam Horm. 2004;68:257-73. doi: 10.1016/S0083-6729(04)68009-5. Vitam Horm. 2004. PMID: 15193458 Review.

5

Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation.

Soldano KL, Jivan A, Nicchitta CV, Gewirth DT. Soldano KL, et al. J Biol Chem. 2003 Nov 28;278(48):48330-8. doi: 10.1074/jbc.M308661200. Epub 2003 Sep 11. J Biol Chem. 2003. PMID: 12970348 Free article.

6

DNA recognition by nuclear receptors.

Claessens F, Gewirth DT. Claessens F, et al. Essays Biochem. 2004;40:59-72. doi: 10.1042/bse0400059. Essays Biochem. 2004. PMID: 15242339 Review.

7

Structures of GRP94-nucleotide complexes reveal mechanistic differences between the hsp90 chaperones.

Dollins DE, Warren JJ, Immormino RM, Gewirth DT. Dollins DE, et al. Among authors: gewirth dt. Mol Cell. 2007 Oct 12;28(1):41-56. doi: 10.1016/j.molcel.2007.08.024. Mol Cell. 2007. PMID: 17936703 Free PMC article.

8

Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.

Immormino RM, Metzger LE 4th, Reardon PN, Dollins DE, Blagg BS, Gewirth DT. Immormino RM, et al. Among authors: gewirth dt. J Mol Biol. 2009 May 22;388(5):1033-42. doi: 10.1016/j.jmb.2009.03.071. Epub 2009 Apr 8. J Mol Biol. 2009. PMID: 19361515 Free PMC article.

9

Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide.

Williams AH, Immormino RM, Gewirth DT, Raetz CR. Williams AH, et al. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10877-82. doi: 10.1073/pnas.0604465103. Epub 2006 Jul 11. Proc Natl Acad Sci U S A. 2006. PMID: 16835299 Free PMC article.

10

Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor.

Shaffer PL, McDonnell DP, Gewirth DT. Shaffer PL, et al. Biochemistry. 2005 Feb 22;44(7):2678-85. doi: 10.1021/bi0477182. Biochemistry. 2005. PMID: 15709781

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