Downer EJ - Search Results

1

The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Delta9-tetrahydrocannabinol in cultured cortical neurons.

Downer EJ, Gowran A, Murphy AC, Campbell VA. Downer EJ, et al. Eur J Pharmacol. 2007 Jun 14;564(1-3):57-65. doi: 10.1016/j.ejphar.2007.02.025. Epub 2007 Feb 22. Eur J Pharmacol. 2007. PMID: 17379209

2

Delta 9-tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor.

Downer E, Boland B, Fogarty M, Campbell V. Downer E, et al. Neuroreport. 2001 Dec 21;12(18):3973-8. doi: 10.1097/00001756-200112210-00024. Neuroreport. 2001. PMID: 11742222

3

A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neurons.

Fogarty MP, Downer EJ, Campbell V. Fogarty MP, et al. Among authors: downer ej. Biochem J. 2003 May 1;371(Pt 3):789-98. doi: 10.1042/BJ20021660. Biochem J. 2003. PMID: 12534344 Free PMC article.

4

Tetrahydrocannabinol-induced neurotoxicity depends on CB1 receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons.

Downer EJ, Fogarty MP, Campbell VA. Downer EJ, et al. Br J Pharmacol. 2003 Oct;140(3):547-57. doi: 10.1038/sj.bjp.0705464. Br J Pharmacol. 2003. PMID: 14522843 Free PMC article.

5

A comparison of the apoptotic effect of Delta(9)-tetrahydrocannabinol in the neonatal and adult rat cerebral cortex.

Downer EJ, Gowran A, Campbell VA. Downer EJ, et al. Brain Res. 2007 Oct 17;1175:39-47. doi: 10.1016/j.brainres.2007.07.076. Epub 2007 Aug 16. Brain Res. 2007. PMID: 17884022

6

Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide.

Lyons A, McQuillan K, Deighan BF, O'Reilly JA, Downer EJ, Murphy AC, Watson M, Piazza A, O'Connell F, Griffin R, Mills KH, Lynch MA. Lyons A, et al. Among authors: downer ej. Brain Behav Immun. 2009 Oct;23(7):1020-7. doi: 10.1016/j.bbi.2009.05.060. Epub 2009 Jun 6. Brain Behav Immun. 2009. PMID: 19501645

7

Phytocannabinoids, CNS cells and development: a dead issue?

Downer EJ, Campbell VA. Downer EJ, et al. Drug Alcohol Rev. 2010 Jan;29(1):91-8. doi: 10.1111/j.1465-3362.2009.00102.x. Drug Alcohol Rev. 2010. PMID: 20078688 Review.

8

The role of cannabinoids in adult neurogenesis.

Prenderville JA, Kelly ÁM, Downer EJ. Prenderville JA, et al. Among authors: downer ej. Br J Pharmacol. 2015 Aug;172(16):3950-63. doi: 10.1111/bph.13186. Epub 2015 Jun 16. Br J Pharmacol. 2015. PMID: 25951750 Free PMC article. Review.

9

A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-gamma modulation.

Downer EJ, Cowley TR, Cox F, Maher FO, Berezin V, Bock E, Lynch MA. Downer EJ, et al. J Neurochem. 2009 Jun;109(5):1516-25. doi: 10.1111/j.1471-4159.2009.06076.x. J Neurochem. 2009. PMID: 19457161 Free article.

10

Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activation in vivo and in vitro.

Lyons A, Lynch AM, Downer EJ, Hanley R, O'Sullivan JB, Smith A, Lynch MA. Lyons A, et al. Among authors: downer ej. J Neurochem. 2009 Sep;110(5):1547-56. doi: 10.1111/j.1471-4159.2009.06253.x. Epub 2009 Jul 15. J Neurochem. 2009. PMID: 19627440 Free article.

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