Winkler WC - Search Results

1

A riboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain.

Roth A, Winkler WC, Regulski EE, Lee BW, Lim J, Jona I, Barrick JE, Ritwik A, Kim JN, Welz R, Iwata-Reuyl D, Breaker RR. Roth A, et al. Among authors: winkler wc. Nat Struct Mol Biol. 2007 Apr;14(4):308-17. doi: 10.1038/nsmb1224. Epub 2007 Mar 25. Nat Struct Mol Biol. 2007. PMID: 17384645

2

An mRNA structure that controls gene expression by binding S-adenosylmethionine.

Winkler WC, Nahvi A, Sudarsan N, Barrick JE, Breaker RR. Winkler WC, et al. Nat Struct Biol. 2003 Sep;10(9):701-7. doi: 10.1038/nsb967. Epub 2003 Aug 10. Nat Struct Biol. 2003. PMID: 12910260

3

Bacterial riboswitches cooperatively bind Ni(2+) or Co(2+) ions and control expression of heavy metal transporters.

Furukawa K, Ramesh A, Zhou Z, Weinberg Z, Vallery T, Winkler WC, Breaker RR. Furukawa K, et al. Among authors: winkler wc. Mol Cell. 2015 Mar 19;57(6):1088-1098. doi: 10.1016/j.molcel.2015.02.009. Mol Cell. 2015. PMID: 25794617 Free PMC article.

4

Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression.

Winkler W, Nahvi A, Breaker RR. Winkler W, et al. Nature. 2002 Oct 31;419(6910):952-6. doi: 10.1038/nature01145. Epub 2002 Oct 16. Nature. 2002. PMID: 12410317

5

An mRNA structure that controls gene expression by binding FMN.

Winkler WC, Cohen-Chalamish S, Breaker RR. Winkler WC, et al. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15908-13. doi: 10.1073/pnas.212628899. Epub 2002 Nov 27. Proc Natl Acad Sci U S A. 2002. PMID: 12456892 Free PMC article.

6

Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria.

Mandal M, Boese B, Barrick JE, Winkler WC, Breaker RR. Mandal M, et al. Among authors: winkler wc. Cell. 2003 May 30;113(5):577-86. doi: 10.1016/s0092-8674(03)00391-x. Cell. 2003. PMID: 12787499 Free article.

7

Control of gene expression by a natural metabolite-responsive ribozyme.

Winkler WC, Nahvi A, Roth A, Collins JA, Breaker RR. Winkler WC, et al. Nature. 2004 Mar 18;428(6980):281-6. doi: 10.1038/nature02362. Nature. 2004. PMID: 15029187

8

New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control.

Barrick JE, Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins J, Lee M, Roth A, Sudarsan N, Jona I, Wickiser JK, Breaker RR. Barrick JE, et al. Among authors: winkler wc. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6421-6. doi: 10.1073/pnas.0308014101. Epub 2004 Apr 19. Proc Natl Acad Sci U S A. 2004. PMID: 15096624 Free PMC article.

9

The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch.

Wickiser JK, Winkler WC, Breaker RR, Crothers DM. Wickiser JK, et al. Among authors: winkler wc. Mol Cell. 2005 Apr 1;18(1):49-60. doi: 10.1016/j.molcel.2005.02.032. Mol Cell. 2005. PMID: 15808508 Free article.

10

Regulation of bacterial gene expression by riboswitches.

Winkler WC, Breaker RR. Winkler WC, et al. Annu Rev Microbiol. 2005;59:487-517. doi: 10.1146/annurev.micro.59.030804.121336. Annu Rev Microbiol. 2005. PMID: 16153177 Review.

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