DeVoss JJ - Search Results

1

Extending the diversity of cytochrome P450 enzymes by DNA family shuffling.

Rosic NN, Huang W, Johnston WA, DeVoss JJ, Gillam EM. Rosic NN, et al. Among authors: devoss jj. Gene. 2007 Jun 15;395(1-2):40-8. doi: 10.1016/j.gene.2007.01.031. Epub 2007 Feb 20. Gene. 2007. PMID: 17400405

2

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EM. Munns AJ, et al. Chem Res Toxicol. 1997 Sep;10(9):1049-58. doi: 10.1021/tx9700836. Chem Res Toxicol. 1997. PMID: 9305589

3

Formation of indigo by recombinant mammalian cytochrome P450.

Gillam EM, Aguinaldo AM, Notley LM, Kim D, Mundkowski RG, Volkov AA, Arnold FH, Soucek P, DeVoss JJ, Guengerich FP. Gillam EM, et al. Among authors: devoss jj. Biochem Biophys Res Commun. 1999 Nov 19;265(2):469-72. doi: 10.1006/bbrc.1999.1702. Biochem Biophys Res Commun. 1999. PMID: 10558891

4

Oxidation of indole by cytochrome P450 enzymes.

Gillam EM, Notley LM, Cai H, De Voss JJ, Guengerich FP. Gillam EM, et al. Biochemistry. 2000 Nov 14;39(45):13817-24. doi: 10.1021/bi001229u. Biochemistry. 2000. PMID: 11076521

5

Cytochrome P450(cin) (CYP176A), isolation, expression, and characterization.

Hawkes DB, Adams GW, Burlingame AL, Ortiz de Montellano PR, De Voss JJ. Hawkes DB, et al. J Biol Chem. 2002 Aug 2;277(31):27725-32. doi: 10.1074/jbc.M203382200. Epub 2002 May 16. J Biol Chem. 2002. PMID: 12016226 Free article.

6

Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).

Davies C, Witham K, Scott JR, Pearson A, DeVoss JJ, Graham SE, Gillam EM. Davies C, et al. Among authors: devoss jj. Drug Metab Dispos. 2004 Apr;32(4):431-6. doi: 10.1124/dmd.32.4.431. Drug Metab Dispos. 2004. PMID: 15039296

7

Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes.

Matthias A, Gillam EM, Penman KG, Matovic NJ, Bone KM, De Voss JJ, Lehmann RP. Matthias A, et al. Chem Biol Interact. 2005 Jun 30;155(1-2):62-70. doi: 10.1016/j.cbi.2005.04.003. Chem Biol Interact. 2005. PMID: 15885678

8

Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites.

Avent KM, DeVoss JJ, Gillam EM. Avent KM, et al. Among authors: devoss jj. Chem Res Toxicol. 2006 Jul;19(7):914-20. doi: 10.1021/tx0600090. Chem Res Toxicol. 2006. PMID: 16841959

9

A shuffled CYP1A library shows both structural integrity and functional diversity.

Johnston WA, Huang W, De Voss JJ, Hayes MA, Gillam EM. Johnston WA, et al. Drug Metab Dispos. 2007 Dec;35(12):2177-85. doi: 10.1124/dmd.107.017939. Epub 2007 Sep 6. Drug Metab Dispos. 2007. PMID: 17823232

10

A shuffled CYP2C library with a high degree of structural integrity and functional versatility.

Huang W, Johnston WA, Hayes MA, De Voss JJ, Gillam EM. Huang W, et al. Arch Biochem Biophys. 2007 Nov 15;467(2):193-205. doi: 10.1016/j.abb.2007.08.023. Epub 2007 Aug 30. Arch Biochem Biophys. 2007. PMID: 17904094

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