Tse AN - Search Results

1

Targeting checkpoint kinase 1 in cancer therapeutics.

Tse AN, Carvajal R, Schwartz GK. Tse AN, et al. Clin Cancer Res. 2007 Apr 1;13(7):1955-60. doi: 10.1158/1078-0432.CCR-06-2793. Clin Cancer Res. 2007. PMID: 17404075 Review.

2

Phase I dose-finding study of weekly docetaxel followed by flavopiridol for patients with advanced solid tumors.

Fornier MN, Rathkopf D, Shah M, Patil S, O'Reilly E, Tse AN, Hudis C, Lefkowitz R, Kelsen DP, Schwartz GK. Fornier MN, et al. Among authors: tse an. Clin Cancer Res. 2007 Oct 1;13(19):5841-6. doi: 10.1158/1078-0432.CCR-07-1218. Clin Cancer Res. 2007. PMID: 17908977 Clinical Trial.

3

Aurora kinases: new targets for cancer therapy.

Carvajal RD, Tse A, Schwartz GK. Carvajal RD, et al. Clin Cancer Res. 2006 Dec 1;12(23):6869-75. doi: 10.1158/1078-0432.CCR-06-1405. Clin Cancer Res. 2006. PMID: 17145803 Review.

4

Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe.

Tse AN, Schwartz GK. Tse AN, et al. Cancer Res. 2004 Sep 15;64(18):6635-44. doi: 10.1158/0008-5472.CAN-04-0841. Cancer Res. 2004. PMID: 15374978

5

CHIR-124, a novel potent inhibitor of Chk1, potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.

Tse AN, Rendahl KG, Sheikh T, Cheema H, Aardalen K, Embry M, Ma S, Moler EJ, Ni ZJ, Lopes de Menezes DE, Hibner B, Gesner TG, Schwartz GK. Tse AN, et al. Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):591-602. doi: 10.1158/1078-0432.CCR-06-1424. Clin Cancer Res. 2007. PMID: 17255282

6

90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.

Tse AN, Sheikh TN, Alan H, Chou TC, Schwartz GK. Tse AN, et al. Mol Pharmacol. 2009 Jan;75(1):124-33. doi: 10.1124/mol.108.050807. Epub 2008 Sep 26. Mol Pharmacol. 2009. PMID: 18820127 Free PMC article.

7

A phase 1 dose-escalation study of irinotecan in combination with 17-allylamino-17-demethoxygeldanamycin in patients with solid tumors.

Tse AN, Klimstra DS, Gonen M, Shah M, Sheikh T, Sikorski R, Carvajal R, Mui J, Tipian C, O'Reilly E, Chung K, Maki R, Lefkowitz R, Brown K, Manova-Todorova K, Wu N, Egorin MJ, Kelsen D, Schwartz GK. Tse AN, et al. Clin Cancer Res. 2008 Oct 15;14(20):6704-11. doi: 10.1158/1078-0432.CCR-08-1006. Clin Cancer Res. 2008. PMID: 18927314 Free PMC article. Clinical Trial.

8

Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

Chung KY, Shia J, Kemeny NE, Shah M, Schwartz GK, Tse A, Hamilton A, Pan D, Schrag D, Schwartz L, Klimstra DS, Fridman D, Kelsen DP, Saltz LB. Chung KY, et al. J Clin Oncol. 2005 Mar 20;23(9):1803-10. doi: 10.1200/JCO.2005.08.037. Epub 2005 Jan 27. J Clin Oncol. 2005. PMID: 15677699

9

Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma.

Shah MA, Ramanathan RK, Ilson DH, Levnor A, D'Adamo D, O'Reilly E, Tse A, Trocola R, Schwartz L, Capanu M, Schwartz GK, Kelsen DP. Shah MA, et al. J Clin Oncol. 2006 Nov 20;24(33):5201-6. doi: 10.1200/JCO.2006.08.0887. J Clin Oncol. 2006. PMID: 17114652 Clinical Trial.

10

A phase II study of flavopiridol (Alvocidib) in combination with docetaxel in refractory, metastatic pancreatic cancer.

Carvajal RD, Tse A, Shah MA, Lefkowitz RA, Gonen M, Gilman-Rosen L, Kortmansky J, Kelsen DP, Schwartz GK, O'Reilly EM. Carvajal RD, et al. Pancreatology. 2009;9(4):404-9. doi: 10.1159/000187135. Epub 2009 May 19. Pancreatology. 2009. PMID: 19451750 Free PMC article. Clinical Trial.

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