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Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.
Murillo MM, Carmona-Cuenca I, Del Castillo G, Ortiz C, Roncero C, Sánchez A, Fernández M, Fabregat I. Murillo MM, et al. Among authors: carmona cuenca i. Biochem J. 2007 Jul 15;405(2):251-9. doi: 10.1042/BJ20061846. Biochem J. 2007. PMID: 17407446 Free PMC article.
The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms.
Sancho P, Bertran E, Caja L, Carmona-Cuenca I, Murillo MM, Fabregat I. Sancho P, et al. Among authors: carmona cuenca i. Biochim Biophys Acta. 2009 Feb;1793(2):253-63. doi: 10.1016/j.bbamcr.2008.09.003. Epub 2008 Sep 24. Biochim Biophys Acta. 2009. PMID: 18848961 Free article.
Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mouse model.
Jimenez S, Torres M, Vizuete M, Sanchez-Varo R, Sanchez-Mejias E, Trujillo-Estrada L, Carmona-Cuenca I, Caballero C, Ruano D, Gutierrez A, Vitorica J. Jimenez S, et al. Among authors: carmona cuenca i. J Biol Chem. 2011 May 27;286(21):18414-25. doi: 10.1074/jbc.M110.209718. Epub 2011 Apr 1. J Biol Chem. 2011. PMID: 21460223 Free PMC article.