Savage DB - Search Results

1

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.

Loos RJ, Franks PW, Francis RW, Barroso I, Gribble FM, Savage DB, Ong KK, O'Rahilly S, Wareham NJ. Loos RJ, et al. Among authors: savage db. Diabetes. 2007 Jul;56(7):1943-7. doi: 10.2337/db07-0055. Epub 2007 Apr 6. Diabetes. 2007. PMID: 17416797 Free PMC article.

2

Resistin / Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans.

Savage DB, Sewter CP, Klenk ES, Segal DG, Vidal-Puig A, Considine RV, O'Rahilly S. Savage DB, et al. Diabetes. 2001 Oct;50(10):2199-202. doi: 10.2337/diabetes.50.10.2199. Diabetes. 2001. PMID: 11574398

3

Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.

Nugent C, Prins JB, Whitehead JP, Savage D, Wentworth JM, Chatterjee VK, O'Rahilly S. Nugent C, et al. Mol Endocrinol. 2001 Oct;15(10):1729-38. doi: 10.1210/mend.15.10.0715. Mol Endocrinol. 2001. PMID: 11579205

4

Leptin: a novel therapeutic role in lipodystrophy.

Savage DB, O'Rahilly S. Savage DB, et al. J Clin Invest. 2002 May;109(10):1285-6. doi: 10.1172/JCI15326. J Clin Invest. 2002. PMID: 12021242 Free PMC article. No abstract available.

5

Isomer-dependent metabolic effects of conjugated linoleic acid: insights from molecular markers sterol regulatory element-binding protein-1c and LXRalpha.

Roche HM, Noone E, Sewter C, Mc Bennett S, Savage D, Gibney MJ, O'Rahilly S, Vidal-Puig AJ. Roche HM, et al. Diabetes. 2002 Jul;51(7):2037-44. doi: 10.2337/diabetes.51.7.2037. Diabetes. 2002. PMID: 12086931

6

The metabolic syndrome: peroxisome proliferator-activated receptor gamma and its therapeutic modulation.

Gurnell M, Savage DB, Chatterjee VK, O'Rahilly S. Gurnell M, et al. Among authors: savage db. J Clin Endocrinol Metab. 2003 Jun;88(6):2412-21. doi: 10.1210/jc.2003-030435. J Clin Endocrinol Metab. 2003. PMID: 12788836 Review.

7

Energy expenditure and adaptive responses to an acute hypercaloric fat load in humans with lipodystrophy.

Savage DB, Murgatroyd PR, Chatterjee VK, O'Rahilly S. Savage DB, et al. J Clin Endocrinol Metab. 2005 Mar;90(3):1446-52. doi: 10.1210/jc.2004-1494. Epub 2004 Dec 21. J Clin Endocrinol Metab. 2005. PMID: 15613417 Clinical Trial.

8

Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma.

Risérus U, Tan GD, Fielding BA, Neville MJ, Currie J, Savage DB, Chatterjee VK, Frayn KN, O'Rahilly S, Karpe F. Risérus U, et al. Among authors: savage db. Diabetes. 2005 May;54(5):1379-84. doi: 10.2337/diabetes.54.5.1379. Diabetes. 2005. PMID: 15855323 Clinical Trial.

9

A clinical approach to severe insulin resistance.

Savage DB, Semple RK, Chatterjee VKK, Wales JKH, Ross RJM, O'Rahilly S. Savage DB, et al. Endocr Dev. 2007;11:122-132. doi: 10.1159/000111067. Endocr Dev. 2007. PMID: 17986832 Review.

10

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.

Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, Shulman GI, Karpe F, Taylor R, Pederson BA, Roach PJ, O'Rahilly S, DePaoli-Roach AA. Savage DB, et al. PLoS Med. 2008 Jan 29;5(1):e27. doi: 10.1371/journal.pmed.0050027. PLoS Med. 2008. PMID: 18232732 Free PMC article.

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