Balzarini J - Search Results

1

Synthesis and biological evaluation of an 123I-labeled bicyclic nucleoside analogue (BCNA) as potential SPECT tracer for VZV-tk reporter gene imaging.

Chitneni SK, Deroose CM, Fonge H, Gijsbers R, Dyubankova N, Balzarini J, Debyser Z, Mortelmans L, Verbruggen AM, Bormans GM. Chitneni SK, et al. Among authors: balzarini j. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3458-62. doi: 10.1016/j.bmcl.2007.03.081. Epub 2007 Mar 30. Bioorg Med Chem Lett. 2007. PMID: 17446073

2

Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography.

Chitneni SK, Deroose CM, Balzarini J, Gijsbers R, Celen SJ, de Groot TJ, Debyser Z, Mortelmans L, Verbruggen AM, Bormans GM. Chitneni SK, et al. Among authors: balzarini j. J Med Chem. 2007 Mar 8;50(5):1041-9. doi: 10.1021/jm060964m. Epub 2007 Feb 14. J Med Chem. 2007. PMID: 17298046

3

A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.

Chitneni SK, Deroose CM, Balzarini J, Gijsbers R, Celen S, Debyser Z, Mortelmans L, Verbruggen AM, Bormans GM. Chitneni SK, et al. Among authors: balzarini j. J Med Chem. 2007 Dec 27;50(26):6627-37. doi: 10.1021/jm700971p. Epub 2007 Nov 30. J Med Chem. 2007. PMID: 18047266

4

Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET.

Deroose CM, Chitneni SK, Gijsbers R, Vermaelen P, Ibrahimi A, Balzarini J, Baekelandt V, Verbruggen A, Nuyts J, Debyser Z, Bormans GM, Mortelmans L. Deroose CM, et al. Among authors: balzarini j. Nucl Med Biol. 2012 Nov;39(8):1266-74. doi: 10.1016/j.nucmedbio.2012.06.014. Epub 2012 Sep 14. Nucl Med Biol. 2012. PMID: 22981986

5

N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action.

Lagoja IM, Pannecouque C, Van Aerschot A, Witvrouw M, Debyser Z, Balzarini J, Herdewijn P, De Clercq E. Lagoja IM, et al. Among authors: balzarini j. J Med Chem. 2003 Apr 10;46(8):1546-53. doi: 10.1021/jm0211117. J Med Chem. 2003. PMID: 12672256

6

Synthesis and evaluation of a (99m)Tc-MAMA-propyl-thymidine complex as a potential probe for in vivo visualization of tumor cell proliferation with SPECT.

Celen S, de Groot T, Balzarini J, Vunckx K, Terwinghe C, Vermaelen P, Van Berckelaer L, Vanbilloen H, Nuyts J, Mortelmans L, Verbruggen A, Bormans G. Celen S, et al. Among authors: balzarini j. Nucl Med Biol. 2007 Apr;34(3):283-91. doi: 10.1016/j.nucmedbio.2007.01.003. Nucl Med Biol. 2007. PMID: 17383578

7

The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture.

Balzarini J, Celen S, Karlsson A, de Groot T, Verbruggen A, Bormans G. Balzarini J, et al. Antivir Chem Chemother. 2006;17(1):17-23. doi: 10.1177/095632020601700103. Antivir Chem Chemother. 2006. PMID: 16542002 Free article.

8

Thymidylate synthase is the principal target enzyme for the cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine against murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 or type 2 thymidine kinase gene.

Balzarini J, De Clercq E, Verbruggen A, Ayusawa D, Shimizu K, Seno T. Balzarini J, et al. Mol Pharmacol. 1987 Sep;32(3):410-6. Mol Pharmacol. 1987. PMID: 2823092

9

Dose-response relationship in cyclophosphamide-treated B-cell lymphoma xenografts monitored with [18F]FDG PET.

Brepoels L, De Saint-Hubert M, Stroobants S, Verhoef G, Balzarini J, Mortelmans L, Mottaghy FM. Brepoels L, et al. Among authors: balzarini j. Eur J Nucl Med Mol Imaging. 2010 Aug;37(9):1688-95. doi: 10.1007/s00259-010-1479-0. Epub 2010 May 12. Eur J Nucl Med Mol Imaging. 2010. PMID: 20461370 Free article.

10

[(18)F]FDG PET monitoring of tumour response to chemotherapy: does [(18)F]FDG uptake correlate with the viable tumour cell fraction?

Spaepen K, Stroobants S, Dupont P, Bormans G, Balzarini J, Verhoef G, Mortelmans L, Vandenberghe P, De Wolf-Peeters C. Spaepen K, et al. Among authors: balzarini j. Eur J Nucl Med Mol Imaging. 2003 May;30(5):682-8. doi: 10.1007/s00259-003-1120-6. Epub 2003 Feb 25. Eur J Nucl Med Mol Imaging. 2003. PMID: 12601498

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