Liao C - Search Results

1

Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase.

Comin MJ, Agbaria R, Ben-Kasus T, Huleihel M, Liao C, Sun G, Nicklaus MC, Deschamps JR, Parrish DA, Marquez VE. Comin MJ, et al. Among authors: liao c. J Am Chem Soc. 2007 May 16;129(19):6216-22. doi: 10.1021/ja0688732. Epub 2007 Apr 24. J Am Chem Soc. 2007. PMID: 17451242

2

D-(+)-iso-methanocarbathymidine: a high-affinity substrate for herpes simplex virus 1 thymidine kinase.

Comin MJ, Vu BC, Boyer PL, Liao C, Hughes SH, Marquez VE. Comin MJ, et al. Among authors: liao c. ChemMedChem. 2008 Jul;3(7):1129-34. doi: 10.1002/cmdc.200800027. ChemMedChem. 2008. PMID: 18399509 Free PMC article.

3

Synthesis and conformational analysis of locked carbocyclic analogues of 1,3-diazepinone riboside, a high-affinity cytidine deaminase inhibitor.

Ludek OR, Schroeder GK, Liao C, Russ PL, Wolfenden R, Marquez VE. Ludek OR, et al. Among authors: liao c. J Org Chem. 2009 Aug 21;74(16):6212-23. doi: 10.1021/jo901127a. J Org Chem. 2009. PMID: 19618900 Free PMC article.

4

Comparison of nine programs predicting pK(a) values of pharmaceutical substances.

Liao C, Nicklaus MC. Liao C, et al. J Chem Inf Model. 2009 Dec;49(12):2801-12. doi: 10.1021/ci900289x. J Chem Inf Model. 2009. PMID: 19961204 Free PMC article.

5

Computer tools in the discovery of HIV-1 integrase inhibitors.

Liao C, Nicklaus MC. Liao C, et al. Future Med Chem. 2010 Jul;2(7):1123-40. doi: 10.4155/fmc.10.193. Future Med Chem. 2010. PMID: 21426160 Free PMC article. Review.

6

Tautomerism and magnesium chelation of HIV-1 integrase inhibitors: a theoretical study.

Liao C, Nicklaus MC. Liao C, et al. ChemMedChem. 2010 Jul 5;5(7):1053-66. doi: 10.1002/cmdc.201000039. ChemMedChem. 2010. PMID: 20533499 Free PMC article.

7

Virtual screening application of a model of full-length HIV-1 integrase complexed with viral DNA.

Liao C, Karki RG, Marchand C, Pommier Y, Nicklaus MC. Liao C, et al. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5361-5. doi: 10.1016/j.bmcl.2007.08.011. Epub 2007 Aug 11. Bioorg Med Chem Lett. 2007. PMID: 17719223

8

The nucleoside analogue D-carba T blocks HIV-1 reverse transcription.

Boyer PL, Vu BC, Ambrose Z, Julias JG, Warnecke S, Liao C, Meier C, Marquez VE, Hughes SH. Boyer PL, et al. Among authors: liao c. J Med Chem. 2009 Sep 10;52(17):5356-64. doi: 10.1021/jm801176e. J Med Chem. 2009. PMID: 19678643 Free PMC article.

9

Authentic HIV-1 integrase inhibitors.

Liao C, Marchand C, Burke TR Jr, Pommier Y, Nicklaus MC. Liao C, et al. Future Med Chem. 2010 Jul;2(7):1107-22. doi: 10.4155/fmc.10.199. Future Med Chem. 2010. PMID: 21426159 Free PMC article. Review.

10

Exploring Potential Binding Modes of Small Drug-like Molecules to the Polo-Box Domain of Human Polo-like Kinase 1.

Liao C, Park JE, Bang JK, Nicklaus MC, Lee KS. Liao C, et al. ACS Med Chem Lett. 2010;1(3):110-114. doi: 10.1021/ml100020e. ACS Med Chem Lett. 2010. PMID: 20625469 Free PMC article.

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