Schweinitz A - Search Results

1

From selective substrate analogue factor Xa inhibitors to dual inhibitors of thrombin and factor Xa. Part 3.

Dönnecke D, Schweinitz A, Stürzebecher A, Steinmetzer P, Schuster M, Stürzebecher U, Nicklisch S, Stürzebecher J, Steinmetzer T. Dönnecke D, et al. Among authors: schweinitz a. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3322-9. doi: 10.1016/j.bmcl.2007.03.105. Epub 2007 Apr 6. Bioorg Med Chem Lett. 2007. PMID: 17462889

2

4-amidinobenzylamine-based inhibitors of urokinase.

Künzel S, Schweinitz A, Reissmann S, Stürzebecher J, Steinmetzer T. Künzel S, et al. Among authors: schweinitz a. Bioorg Med Chem Lett. 2002 Feb 25;12(4):645-8. doi: 10.1016/s0960-894x(01)00815-0. Bioorg Med Chem Lett. 2002. PMID: 11844691

3

Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase.

Steinmetzer T, Schweinitz A, Stürzebecher A, Dönnecke D, Uhland K, Schuster O, Steinmetzer P, Müller F, Friedrich R, Than ME, Bode W, Stürzebecher J. Steinmetzer T, et al. Among authors: schweinitz a. J Med Chem. 2006 Jul 13;49(14):4116-26. doi: 10.1021/jm051272l. J Med Chem. 2006. PMID: 16821772

4

New substrate analogue inhibitors of factor Xa containing 4-amidinobenzylamide as P1 residue: part 1.

Schweinitz A, Stürzebecher A, Stürzebecher U, Schuster O, Stürzebecher J, Steinmetzer T. Schweinitz A, et al. Med Chem. 2006 Jul;2(4):349-61. doi: 10.2174/157340606777724040. Med Chem. 2006. PMID: 16848746

5

Highly potent and selective substrate analogue factor Xa inhibitors containing D-homophenylalanine analogues as P3 residue: part 2.

Stürzebecher A, Dönnecke D, Schweinitz A, Schuster O, Steinmetzer P, Stürzebecher U, Kotthaus J, Clement B, Stürzebecher J, Steinmetzer T. Stürzebecher A, et al. Among authors: schweinitz a. ChemMedChem. 2007 Jul;2(7):1043-53. doi: 10.1002/cmdc.200700031. ChemMedChem. 2007. PMID: 17541992

6

Modification of the N-terminal sulfonyl residue in 3-amidinophenylalanine-based matriptase inhibitors.

Steinmetzer T, Dönnecke D, Korsonewski M, Neuwirth C, Steinmetzer P, Schulze A, Saupe SM, Schweinitz A. Steinmetzer T, et al. Among authors: schweinitz a. Bioorg Med Chem Lett. 2009 Jan 1;19(1):67-73. doi: 10.1016/j.bmcl.2008.11.019. Epub 2008 Nov 13. Bioorg Med Chem Lett. 2009. PMID: 19036586

7

Incorporation of neutral C-terminal residues in 3-amidinophenylalanine-derived matriptase inhibitors.

Schweinitz A, Dönnecke D, Ludwig A, Steinmetzer P, Schulze A, Kotthaus J, Wein S, Clement B, Steinmetzer T. Schweinitz A, et al. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1960-5. doi: 10.1016/j.bmcl.2009.02.047. Epub 2009 Feb 14. Bioorg Med Chem Lett. 2009. PMID: 19250826

8

Structure-activity relationships of new NAPAP-analogs.

Steinmetzer T, Schweinitz A, Künzel S, Wikström P, Hauptmann J, Stürzebecher J. Steinmetzer T, et al. Among authors: schweinitz a. J Enzyme Inhib Med Chem. 2002 Apr;17(2):241-9. J Enzyme Inhib Med Chem. 2002. PMID: 12420761

9

Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents.

Schweinitz A, Steinmetzer T, Banke IJ, Arlt MJ, Stürzebecher A, Schuster O, Geissler A, Giersiefen H, Zeslawska E, Jacob U, Krüger A, Stürzebecher J. Schweinitz A, et al. J Biol Chem. 2004 Aug 6;279(32):33613-22. doi: 10.1074/jbc.M314151200. Epub 2004 May 18. J Biol Chem. 2004. PMID: 15150279 Free article.

10

3-Amidinophenylalanine-based inhibitors of urokinase.

Stürzebecher J, Vieweg H, Steinmetzer T, Schweinitz A, Stubbs MT, Renatus M, Wikström P. Stürzebecher J, et al. Among authors: schweinitz a. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3147-52. doi: 10.1016/s0960-894x(99)00541-7. Bioorg Med Chem Lett. 1999. PMID: 10560742

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