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New platinum(II) complexes containing both an O,O'-chelated acetylacetonate ligand and a sulfur ligand in the platinum coordination sphere induce apoptosis in HeLa cervical carcinoma cells.
Muscella A, Calabriso N, De Pascali SA, Urso L, Ciccarese A, Fanizzi FP, Migoni D, Marsigliante S. Muscella A, et al. Among authors: fanizzi fp. Biochem Pharmacol. 2007 Jun 30;74(1):28-40. doi: 10.1016/j.bcp.2007.03.027. Epub 2007 Mar 31. Biochem Pharmacol. 2007. PMID: 17481588
A rare example of three abundant conformers in one retro model of the cisplatin-DNA d(GpG) intrastrand cross link. Unambiguous evidence that guanine O6 to carrier amine ligand hydrogen bonding is not important. possible effect of the Lippard base pair step adjacent to the lesion on carrier ligand hydrogen bonding in DNA adducts.
Sullivan ST, Ciccarese A, Fanizzi FP, Marzilli LG. Sullivan ST, et al. Among authors: fanizzi fp. J Am Chem Soc. 2001 Sep 26;123(38):9345-55. doi: 10.1021/ja010483m. J Am Chem Soc. 2001. PMID: 11562217
176 results