Yun JK - Search Results

1

Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells.

Francy JM, Nag A, Conroy EJ, Hengst JA, Yun JK. Francy JM, et al. Among authors: yun jk. Biochim Biophys Acta. 2007 Apr;1769(4):253-65. doi: 10.1016/j.bbaexp.2007.03.005. Epub 2007 Apr 3. Biochim Biophys Acta. 2007. PMID: 17482291

2

Discovery and evaluation of inhibitors of human sphingosine kinase.

French KJ, Schrecengost RS, Lee BD, Zhuang Y, Smith SN, Eberly JL, Yun JK, Smith CD. French KJ, et al. Among authors: yun jk. Cancer Res. 2003 Sep 15;63(18):5962-9. Cancer Res. 2003. PMID: 14522923

3

Antitumor activity of sphingosine kinase inhibitors.

French KJ, Upson JJ, Keller SN, Zhuang Y, Yun JK, Smith CD. French KJ, et al. Among authors: yun jk. J Pharmacol Exp Ther. 2006 Aug;318(2):596-603. doi: 10.1124/jpet.106.101345. Epub 2006 Apr 21. J Pharmacol Exp Ther. 2006. PMID: 16632640

4

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains.

Fox TE, Houck KL, O'Neill SM, Nagarajan M, Stover TC, Pomianowski PT, Unal O, Yun JK, Naides SJ, Kester M. Fox TE, et al. Among authors: yun jk. J Biol Chem. 2007 Apr 27;282(17):12450-7. doi: 10.1074/jbc.M700082200. Epub 2007 Feb 17. J Biol Chem. 2007. PMID: 17308302 Free article.

5

Sphingosine 1-phosphate has dual functions in the regulation of endothelial cell permeability and Ca2+ metabolism.

Itagaki K, Yun JK, Hengst JA, Yatani A, Hauser CJ, Spolarics Z, Deitch EA. Itagaki K, et al. Among authors: yun jk. J Pharmacol Exp Ther. 2007 Oct;323(1):186-91. doi: 10.1124/jpet.107.121210. Epub 2007 Jul 12. J Pharmacol Exp Ther. 2007. PMID: 17626797

6

Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive targets for novel pharmacological interventions.

Bayerl MG, Bruggeman RD, Conroy EJ, Hengst JA, King TS, Jimenez M, Claxton DF, Yun JK. Bayerl MG, et al. Among authors: yun jk. Leuk Lymphoma. 2008 May;49(5):948-54. doi: 10.1080/10428190801911654. Leuk Lymphoma. 2008. PMID: 18452097

7

Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition.

Hengst JA, Guilford JM, Fox TE, Wang X, Conroy EJ, Yun JK. Hengst JA, et al. Among authors: yun jk. Arch Biochem Biophys. 2009 Dec;492(1-2):62-73. doi: 10.1016/j.abb.2009.09.013. Epub 2009 Sep 24. Arch Biochem Biophys. 2009. PMID: 19782042 Free PMC article.

8

Enhancement of sphingosine kinase 1 catalytic activity by deletion of 21 amino acids from the COOH-terminus.

Hengst JA, Guilford JM, Conroy EJ, Wang X, Yun JK. Hengst JA, et al. Among authors: yun jk. Arch Biochem Biophys. 2010 Feb 1;494(1):23-31. doi: 10.1016/j.abb.2009.11.006. Epub 2009 Nov 13. Arch Biochem Biophys. 2010. PMID: 19914200 Free PMC article.

9

Synthesis and bioactivity of sphingosine kinase inhibitors and their novel aspirinyl conjugated analogs.

Sharma AK, Sk UH, Gimbor MA, Hengst JA, Wang X, Yun J, Amin S. Sharma AK, et al. Eur J Med Chem. 2010 Sep;45(9):4149-56. doi: 10.1016/j.ejmech.2010.06.005. Epub 2010 Jun 12. Eur J Med Chem. 2010. PMID: 20598402

10

Selenium-containing analogs of SAHA induce cytotoxicity in lung cancer cells.

Karelia N, Desai D, Hengst JA, Amin S, Rudrabhatla SV, Yun J. Karelia N, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6816-9. doi: 10.1016/j.bmcl.2010.08.113. Epub 2010 Aug 27. Bioorg Med Chem Lett. 2010. PMID: 20855208 Free PMC article.

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