Cerniglia GJ - Search Results

1

Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.

Jiang Z, Pore N, Cerniglia GJ, Mick R, Georgescu MM, Bernhard EJ, Hahn SM, Gupta AK, Maity A. Jiang Z, et al. Among authors: cerniglia gj. Cancer Res. 2007 May 1;67(9):4467-73. doi: 10.1158/0008-5472.CAN-06-3398. Cancer Res. 2007. PMID: 17483362

2

EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms.

Pore N, Jiang Z, Gupta A, Cerniglia G, Kao GD, Maity A. Pore N, et al. Cancer Res. 2006 Mar 15;66(6):3197-204. doi: 10.1158/0008-5472.CAN-05-3090. Cancer Res. 2006. PMID: 16540671

3

Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction.

Gupta AK, McKenna WG, Weber CN, Feldman MD, Goldsmith JD, Mick R, Machtay M, Rosenthal DI, Bakanauskas VJ, Cerniglia GJ, Bernhard EJ, Weber RS, Muschel RJ. Gupta AK, et al. Among authors: cerniglia gj. Clin Cancer Res. 2002 Mar;8(3):885-92. Clin Cancer Res. 2002. PMID: 11895923 Clinical Trial.

4

Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival.

Shi Y, Wu J, Mick R, Cerniglia GJ, Cohen-Jonathan E, Rhim JS, Koch CJ, Bernhard EJ. Shi Y, et al. Among authors: cerniglia gj. Prostate. 2005 Jan 1;62(1):69-82. doi: 10.1002/pros.20122. Prostate. 2005. PMID: 15389805

5

HIV protease inhibitors block Akt signaling and radiosensitize tumor cells both in vitro and in vivo.

Gupta AK, Cerniglia GJ, Mick R, McKenna WG, Muschel RJ. Gupta AK, et al. Among authors: cerniglia gj. Cancer Res. 2005 Sep 15;65(18):8256-65. doi: 10.1158/0008-5472.CAN-05-1220. Cancer Res. 2005. PMID: 16166302

6

Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy.

Pore N, Gupta AK, Cerniglia GJ, Jiang Z, Bernhard EJ, Evans SM, Koch CJ, Hahn SM, Maity A. Pore N, et al. Among authors: cerniglia gj. Cancer Res. 2006 Sep 15;66(18):9252-9. doi: 10.1158/0008-5472.CAN-06-1239. Cancer Res. 2006. PMID: 16982770

7

HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells.

Pore N, Gupta AK, Cerniglia GJ, Maity A. Pore N, et al. Among authors: cerniglia gj. Neoplasia. 2006 Nov;8(11):889-95. doi: 10.1593/neo.06535. Neoplasia. 2006. PMID: 17132220 Free PMC article.

8

Bortezomib sensitizes human head and neck carcinoma cells SQ20B to radiation.

Weber CN, Cerniglia GJ, Maity A, Gupta AK. Weber CN, et al. Among authors: cerniglia gj. Cancer Biol Ther. 2007 Feb;6(2):156-9. doi: 10.4161/cbt.6.2.3556. Epub 2007 Mar 1. Cancer Biol Ther. 2007. PMID: 17224644 Free article.

9

The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response.

Gupta AK, Li B, Cerniglia GJ, Ahmed MS, Hahn SM, Maity A. Gupta AK, et al. Among authors: cerniglia gj. Neoplasia. 2007 Apr;9(4):271-8. doi: 10.1593/neo.07124. Neoplasia. 2007. PMID: 17460771 Free PMC article.

10

Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines.

Bernhard EJ, Stanbridge EJ, Gupta S, Gupta AK, Soto D, Bakanauskas VJ, Cerniglia GJ, Muschel RJ, McKenna WG. Bernhard EJ, et al. Among authors: cerniglia gj. Cancer Res. 2000 Dec 1;60(23):6597-600. Cancer Res. 2000. PMID: 11118040

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