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Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.
Pirinen E, Kuulasmaa T, Pietilä M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamäki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen AL, Ylä-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Jänne J, Laakso M. Pirinen E, et al. Mol Cell Biol. 2007 Jul;27(13):4953-67. doi: 10.1128/MCB.02034-06. Epub 2007 May 7. Mol Cell Biol. 2007. PMID: 17485446 Free PMC article.
Animal disease models generated by genetic engineering of polyamine metabolism.
Jänne J, Alhonen L, Keinänen TA, Pietilä M, Uimari A, Pirinen E, Hyvönen MT, Järvinen A. Jänne J, et al. Among authors: pirinen e. J Cell Mol Med. 2005 Oct-Dec;9(4):865-82. doi: 10.1111/j.1582-4934.2005.tb00385.x. J Cell Mol Med. 2005. PMID: 16364196 Free PMC article. Review.
Genetic manipulation of polyamine catabolism in rodents.
Jänne J, Alhonen L, Pietilä M, Keinänen TA, Uimari A, Hyvönen MT, Pirinen E, Järvinen A. Jänne J, et al. Among authors: pirinen e. J Biochem. 2006 Feb;139(2):155-60. doi: 10.1093/jb/mvj035. J Biochem. 2006. PMID: 16452302 Review.
Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.
Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J. Niiranen K, et al. Among authors: pirinen e. J Cell Mol Med. 2006 Oct-Dec;10(4):933-45. doi: 10.1111/j.1582-4934.2006.tb00536.x. J Cell Mol Med. 2006. PMID: 17125596 Free article.
Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.
Vuohelainen S, Pirinen E, Cerrada-Gimenez M, Keinänen TA, Uimari A, Pietilä M, Khomutov AR, Jänne J, Alhonen L. Vuohelainen S, et al. Among authors: pirinen e. J Cell Mol Med. 2010 Jun;14(6B):1683-92. doi: 10.1111/j.1582-4934.2009.00808.x. Epub 2009 Jun 16. J Cell Mol Med. 2010. PMID: 19538475 Free PMC article.
68 results