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The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.
McCarthy C, Shepherd D, Fleire S, Stronge VS, Koch M, Illarionov PA, Bossi G, Salio M, Denkberg G, Reddington F, Tarlton A, Reddy BG, Schmidt RR, Reiter Y, Griffiths GM, van der Merwe PA, Besra GS, Jones EY, Batista FD, Cerundolo V. McCarthy C, et al. Among authors: besra gs. J Exp Med. 2007 May 14;204(5):1131-44. doi: 10.1084/jem.20062342. Epub 2007 May 7. J Exp Med. 2007. PMID: 17485514 Free PMC article.
The crystal structure of human CD1b with a bound bacterial glycolipid.
Batuwangala T, Shepherd D, Gadola SD, Gibson KJ, Zaccai NR, Fersht AR, Besra GS, Cerundolo V, Jones EY. Batuwangala T, et al. Among authors: besra gs. J Immunol. 2004 Feb 15;172(4):2382-8. doi: 10.4049/jimmunol.172.4.2382. J Immunol. 2004. PMID: 14764708
CD1d-restricted T cell activation by nonlipidic small molecules.
Van Rhijn I, Young DC, Im JS, Levery SB, Illarionov PA, Besra GS, Porcelli SA, Gumperz J, Cheng TY, Moody DB. Van Rhijn I, et al. Among authors: besra gs. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13578-83. doi: 10.1073/pnas.0402838101. Epub 2004 Sep 1. Proc Natl Acad Sci U S A. 2004. PMID: 15342907 Free PMC article.
508 results