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Open-label, controlled, phase 2 clinical trial assessing the safety, efficacy, and pharmacokinetics of INM004 in pediatric patients with Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome.
Fayad A, Principi I, Balestracci A, Alconcher L, Coccia P, Adragna M, Amoreo O, Bettendorff MC, Blumetti MV, Bonany P, Tonfi MLF, Flynn L, Ghezzi L, Montero J, Ramírez F, Seminara C, Suarez Á, Spizzirri AP, Rivas M, Pichel M, Zylberman V, Spatz L, Massa C, Valerio M, Sanguineti S, Colonna M, Roubicek I, Goldbaum F; INM004 Study Group. Fayad A, et al. Among authors: massa c. Pediatr Nephrol. 2024 Nov 12. doi: 10.1007/s00467-024-06583-3. Online ahead of print. Pediatr Nephrol. 2024. PMID: 39528845
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis.
Rapacciuolo P, Finamore C, Giorgio CD, Fiorillo B, Massa C, Urbani G, Marchianò S, Bordoni M, Cassiano C, Morretta E, Spinelli L, Lupia A, Moraca F, Biagioli M, Sepe V, Monti MC, Catalanotti B, Fiorucci S, Zampella A. Rapacciuolo P, et al. Among authors: massa c. J Med Chem. 2024 Oct 24;67(20):18334-18355. doi: 10.1021/acs.jmedchem.4c01651. Epub 2024 Oct 9. J Med Chem. 2024. PMID: 39382988
147 results