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MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML.
Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, Schlenk RF, Dohner K, Hinrichsen T, Rudolph C, Schambach A, Baum C, Schlegelberger B, Dohner H, Ganser A, Humphries RK. Heuser M, et al. Among authors: kuchenbauer f. Blood. 2007 Sep 1;110(5):1639-47. doi: 10.1182/blood-2007-03-080523. Epub 2007 May 9. Blood. 2007. PMID: 17494859 Free article. Clinical Trial.
Linkage of the potent leukemogenic activity of Meis1 to cell-cycle entry and transcriptional regulation of cyclin D3.
Argiropoulos B, Yung E, Xiang P, Lo CY, Kuchenbauer F, Palmqvist L, Reindl C, Heuser M, Sekulovic S, Rosten P, Muranyi A, Goh SL, Featherstone M, Humphries RK. Argiropoulos B, et al. Among authors: kuchenbauer f. Blood. 2010 May 20;115(20):4071-82. doi: 10.1182/blood-2009-06-225573. Epub 2010 Mar 17. Blood. 2010. PMID: 20237320 Free article.
Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells.
Kuchenbauer F, Mah SM, Heuser M, McPherson A, Rüschmann J, Rouhi A, Berg T, Bullinger L, Argiropoulos B, Morin RD, Lai D, Starczynowski DT, Karsan A, Eaves CJ, Watahiki A, Wang Y, Aparicio SA, Ganser A, Krauter J, Döhner H, Döhner K, Marra MA, Camargo FD, Palmqvist L, Buske C, Humphries RK. Kuchenbauer F, et al. Blood. 2011 Sep 22;118(12):3350-8. doi: 10.1182/blood-2010-10-312454. Epub 2011 May 31. Blood. 2011. PMID: 21628414 Free article.
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.
Heuser M, Yun H, Berg T, Yung E, Argiropoulos B, Kuchenbauer F, Park G, Hamwi I, Palmqvist L, Lai CK, Leung M, Lin G, Chaturvedi A, Thakur BK, Iwasaki M, Bilenky M, Thiessen N, Robertson G, Hirst M, Kent D, Wilson NK, Göttgens B, Eaves C, Cleary ML, Marra M, Ganser A, Humphries RK. Heuser M, et al. Among authors: kuchenbauer f. Cancer Cell. 2011 Jul 12;20(1):39-52. doi: 10.1016/j.ccr.2011.06.020. Cancer Cell. 2011. PMID: 21741595 Free PMC article.
Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene.
Lai CK, Moon Y, Kuchenbauer F, Starzcynowski DT, Argiropoulos B, Yung E, Beer P, Schwarzer A, Sharma A, Park G, Leung M, Lin G, Vollett S, Fung S, Eaves CJ, Karsan A, Weng AP, Humphries RK, Heuser M. Lai CK, et al. Among authors: kuchenbauer f. PLoS One. 2014 Nov 17;9(11):e112671. doi: 10.1371/journal.pone.0112671. eCollection 2014. PLoS One. 2014. PMID: 25401736 Free PMC article.
MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia.
Krowiorz K, Ruschmann J, Lai C, Ngom M, Maetzig T, Martins V, Scheffold A, Schneider E, Pochert N, Miller C, Palmqvist L, Staffas A, Mulaw M, Bohl SR, Buske C, Heuser M, Kraus J, O'Neill K, Hansen CL, Petriv OI, Kestler H, Döhner H, Bullinger L, Döhner K, Humphries RK, Rouhi A, Kuchenbauer F. Krowiorz K, et al. Among authors: kuchenbauer f. Blood Cancer J. 2016 Dec 9;6(12):e508. doi: 10.1038/bcj.2016.110. Blood Cancer J. 2016. PMID: 27935579 Free PMC article. No abstract available.
99 results