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Page 1
MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML.
Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, Schlenk RF, Dohner K, Hinrichsen T, Rudolph C, Schambach A, Baum C, Schlegelberger B, Dohner H, Ganser A, Humphries RK. Heuser M, et al. Among authors: yung e. Blood. 2007 Sep 1;110(5):1639-47. doi: 10.1182/blood-2007-03-080523. Epub 2007 May 9. Blood. 2007. PMID: 17494859 Free article. Clinical Trial.
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.
Heuser M, Yun H, Berg T, Yung E, Argiropoulos B, Kuchenbauer F, Park G, Hamwi I, Palmqvist L, Lai CK, Leung M, Lin G, Chaturvedi A, Thakur BK, Iwasaki M, Bilenky M, Thiessen N, Robertson G, Hirst M, Kent D, Wilson NK, Göttgens B, Eaves C, Cleary ML, Marra M, Ganser A, Humphries RK. Heuser M, et al. Among authors: yung e. Cancer Cell. 2011 Jul 12;20(1):39-52. doi: 10.1016/j.ccr.2011.06.020. Cancer Cell. 2011. PMID: 21741595 Free PMC article.
Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene.
Lai CK, Moon Y, Kuchenbauer F, Starzcynowski DT, Argiropoulos B, Yung E, Beer P, Schwarzer A, Sharma A, Park G, Leung M, Lin G, Vollett S, Fung S, Eaves CJ, Karsan A, Weng AP, Humphries RK, Heuser M. Lai CK, et al. Among authors: yung e. PLoS One. 2014 Nov 17;9(11):e112671. doi: 10.1371/journal.pone.0112671. eCollection 2014. PLoS One. 2014. PMID: 25401736 Free PMC article.
In-depth characterization of the microRNA transcriptome in a leukemia progression model.
Kuchenbauer F, Morin RD, Argiropoulos B, Petriv OI, Griffith M, Heuser M, Yung E, Piper J, Delaney A, Prabhu AL, Zhao Y, McDonald H, Zeng T, Hirst M, Hansen CL, Marra MA, Humphries RK. Kuchenbauer F, et al. Among authors: yung e. Genome Res. 2008 Nov;18(11):1787-97. doi: 10.1101/gr.077578.108. Epub 2008 Oct 10. Genome Res. 2008. PMID: 18849523 Free PMC article.
Elucidating the importance and regulation of key enhancers for human MEIS1 expression.
Xiang P, Yang X, Escano L, Dhillon I, Schneider E, Clemans-Gibbon J, Wei W, Wong J, Wang SX, Tam D, Deng Y, Yung E, Morin GB, Hoodless PA, Hirst M, Karsan A, Kuchenbauer F, Humphries RK, Rouhi A. Xiang P, et al. Among authors: yung e. Leukemia. 2022 Aug;36(8):1980-1989. doi: 10.1038/s41375-022-01602-4. Epub 2022 May 27. Leukemia. 2022. PMID: 35624144 Free PMC article.
113 results