Andersson TB - Search Results

1

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis.

Kindmark A, Jawaid A, Harbron CG, Barratt BJ, Bengtsson OF, Andersson TB, Carlsson S, Cederbrant KE, Gibson NJ, Armstrong M, Lagerström-Fermér ME, Dellsén A, Brown EM, Thornton M, Dukes C, Jenkins SC, Firth MA, Harrod GO, Pinel TH, Billing-Clason SM, Cardon LR, March RE. Kindmark A, et al. Among authors: andersson tb. Pharmacogenomics J. 2008 Jun;8(3):186-95. doi: 10.1038/sj.tpj.6500458. Epub 2007 May 15. Pharmacogenomics J. 2008. PMID: 17505501

2

Prediction of drug-induced liver injury in humans by using in vitro methods: the case of ximelagatran.

Kenne K, Skanberg I, Glinghammar B, Berson A, Pessayre D, Flinois JP, Beaune P, Edebert I, Pohl CD, Carlsson S, Andersson TB. Kenne K, et al. Among authors: andersson tb. Toxicol In Vitro. 2008 Apr;22(3):730-46. doi: 10.1016/j.tiv.2007.11.014. Epub 2007 Dec 3. Toxicol In Vitro. 2008. PMID: 18191936

3

Investigations into the liver effects of ximelagatran using high content screening of primary human hepatocyte cultures.

Ainscow EK, Pilling JE, Brown NM, Orme AT, Sullivan M, Hargreaves AC, Cooke EL, Sullivan E, Carlsson S, Andersson TB. Ainscow EK, et al. Among authors: andersson tb. Expert Opin Drug Saf. 2008 Jul;7(4):351-65. doi: 10.1517/14740338.7.4.351. Expert Opin Drug Saf. 2008. PMID: 18613800

4

Drug-induced liver injury in humans: the case of ximelagatran.

Keisu M, Andersson TB. Keisu M, et al. Among authors: andersson tb. Handb Exp Pharmacol. 2010;(196):407-18. doi: 10.1007/978-3-642-00663-0_13. Handb Exp Pharmacol. 2010. PMID: 20020269 Review.

5

Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions.

Bredberg E, Andersson TB, Frison L, Thuresson A, Johansson S, Eriksson-Lepkowska M, Larsson M, Eriksson UG. Bredberg E, et al. Among authors: andersson tb. Clin Pharmacokinet. 2003;42(8):765-77. doi: 10.2165/00003088-200342080-00005. Clin Pharmacokinet. 2003. PMID: 12846597 Clinical Trial.

6

Investigation of the involvement of P-glycoprotein and multidrug resistance-associated protein 2 in the efflux of ximelagatran and its metabolites by using short hairpin RNA knockdown in Caco-2 cells.

Darnell M, Karlsson JE, Owen A, Hidalgo IJ, Li J, Zhang W, Andersson TB. Darnell M, et al. Among authors: andersson tb. Drug Metab Dispos. 2010 Mar;38(3):491-7. doi: 10.1124/dmd.109.029967. Epub 2009 Dec 18. Drug Metab Dispos. 2010. PMID: 20023051

7

Hepatic disposition of ximelagatran and its metabolites in pig; prediction of the impact of membrane transporters through a simple disposition model.

Sjögren E, Bredberg U, Allard E, Arvidsson B, Bergquist J, Andersson TB, Lennernäs H. Sjögren E, et al. Among authors: andersson tb. Pharm Res. 2010 Apr;27(4):597-607. doi: 10.1007/s11095-009-0016-y. Epub 2010 Feb 6. Pharm Res. 2010. PMID: 20140637

8

Proteomics-Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight.

Wegler C, Prieto Garcia L, Klinting S, Robertsen I, Wiśniewski JR, Hjelmesaeth J, Åsberg A, Jansson-Löfmark R, Andersson TB, Artursson P. Wegler C, et al. Among authors: andersson tb. Clin Pharmacol Ther. 2021 Mar;109(3):762-771. doi: 10.1002/cpt.2056. Epub 2020 Oct 18. Clin Pharmacol Ther. 2021. PMID: 32970864 Free PMC article.

9

HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans.

Kanebratt KP, Andersson TB. Kanebratt KP, et al. Among authors: andersson tb. Drug Metab Dispos. 2008 Jan;36(1):137-45. doi: 10.1124/dmd.107.017418. Epub 2007 Oct 22. Drug Metab Dispos. 2008. PMID: 17954527

10

The application of HepRG cells in evaluation of cytochrome P450 induction properties of drug compounds.

Andersson TB. Andersson TB. Methods Mol Biol. 2010;640:375-87. doi: 10.1007/978-1-60761-688-7_20. Methods Mol Biol. 2010. PMID: 20645063

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