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Page 1
Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists.
Pégurier C, Collart P, Danhaive P, Defays S, Gillard M, Gilson F, Kogej T, Pasau P, Van Houtvin N, Van Thuyne M, van Keulen B. Pégurier C, et al. Among authors: van houtvin n. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4228-31. doi: 10.1016/j.bmcl.2007.05.035. Epub 2007 May 17. Bioorg Med Chem Lett. 2007. PMID: 17532633
Discovery of new C3aR ligands. Part 2: amino-piperidine derivatives.
Denonne F, Binet S, Burton M, Collart P, Defays S, Dipesa A, Eckert M, Giannaras A, Kumar S, Levine B, Nicolas JM, Pasau P, Pégurier C, Preda D, Van houtvin N, Volosov A, Zou D. Denonne F, et al. Among authors: van houtvin n. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3262-5. doi: 10.1016/j.bmcl.2007.04.023. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17459702
Acetamide scanning around bicyclic thiazoles: SAR at the H₃ receptor.
Denonne F, Célanire S, Christophe B, Defays S, Delaunoy C, Delporte ML, Detrait E, Durieu V, Gillard M, Lamberty Y, Lorent G, Nicolas JM, Vanbellinghen A, Van Houtvin N, Provins L. Denonne F, et al. Among authors: van houtvin n. ChemMedChem. 2011 Sep 5;6(9):1559-65. doi: 10.1002/cmdc.201100248. Epub 2011 Jul 14. ChemMedChem. 2011. PMID: 21761567 No abstract available.
Lead optimization of thiazolo[5,4-c]piperidines: 3-cyclobutoxy linker as a key spacer for H(3)R inverse agonists.
Provins L, Denonne F, Célanire S, Christophe B, Defays S, Delaunoy C, Delporte ML, Demaude T, Durieu V, Gillard M, Hubert D, Lamberty Y, Lorent G, Valade A, Vanbellinghen A, Van Houtvin N. Provins L, et al. Among authors: van houtvin n. ChemMedChem. 2012 Dec;7(12):2087-92. doi: 10.1002/cmdc.201200406. Epub 2012 Oct 5. ChemMedChem. 2012. PMID: 23042668
Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. Among authors: van houtvin n. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064
Phenyl-oxazoles, a new family of inverse agonists at the H(3) histamine receptor.
Denonne F, Atienzar F, Célanire S, Christophe B, Delannois F, Delaunoy C, Delporte ML, Durieu V, Gillard M, Lallemand B, Lamberty Y, Lorent G, Vanbellinghen A, Van Houtvin N, Verbois V, Provins L. Denonne F, et al. Among authors: van houtvin n. ChemMedChem. 2010 Feb 1;5(2):206-12. doi: 10.1002/cmdc.200900446. ChemMedChem. 2010. PMID: 20043314 No abstract available.
Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase.
Ernst G, Akuma D, Au V, Buchler IP, Byers S, Carr GV, Defays S, de León P, Demaude T, DePasquale M, Durieu V, Huang Y, Jigorel E, Kimos M, Kolobova A, Montel F, Moureau F, Poslusney M, Swinnen D, Vandergeten MC, Van Houtvin N, Wei H, White N, Wood M, Barrow JC. Ernst G, et al. Among authors: van houtvin n. ACS Med Chem Lett. 2019 Oct 22;10(11):1573-1578. doi: 10.1021/acsmedchemlett.9b00345. eCollection 2019 Nov 14. ACS Med Chem Lett. 2019. PMID: 32038769 Free PMC article.