Stephens DL - Search Results

1

TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells.

Buczynski MW, Stephens DL, Bowers-Gentry RC, Grkovich A, Deems RA, Dennis EA. Buczynski MW, et al. Among authors: stephens dl. J Biol Chem. 2007 Aug 3;282(31):22834-47. doi: 10.1074/jbc.M701831200. Epub 2007 May 29. J Biol Chem. 2007. PMID: 17535806 Free article.

2

Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry.

Hsu YH, Burke JE, Stephens DL, Deems RA, Li S, Asmus KM, Woods VL Jr, Dennis EA. Hsu YH, et al. Among authors: stephens dl. J Biol Chem. 2008 Apr 11;283(15):9820-7. doi: 10.1074/jbc.M708143200. Epub 2008 Jan 21. J Biol Chem. 2008. PMID: 18211893 Free PMC article.

3

Differential inhibition of group IVA and group VIA phospholipases A2 by 2-oxoamides.

Stephens D, Barbayianni E, Constantinou-Kokotou V, Peristeraki A, Six DA, Cooper J, Harkewicz R, Deems RA, Dennis EA, Kokotos G. Stephens D, et al. J Med Chem. 2006 May 4;49(9):2821-8. doi: 10.1021/jm050993h. J Med Chem. 2006. PMID: 16640343 Free PMC article.

4

PGE2 release is independent of upregulation of Group V phospholipase A2 during long-term stimulation of P388D1 cells with LPS.

Kessen UA, Schaloske RH, Stephens DL, Killermann Lucas K, Dennis EA. Kessen UA, et al. Among authors: stephens dl. J Lipid Res. 2005 Nov;46(11):2488-96. doi: 10.1194/jlr.M500325-JLR200. Epub 2005 Sep 8. J Lipid Res. 2005. PMID: 16150819 Free article.

5

An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis.

Gupta S, Maurya MR, Stephens DL, Dennis EA, Subramaniam S. Gupta S, et al. Among authors: stephens dl. Biophys J. 2009 Jun 3;96(11):4542-51. doi: 10.1016/j.bpj.2009.03.011. Biophys J. 2009. PMID: 19486676 Free PMC article.

6

Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2.

Six DA, Barbayianni E, Loukas V, Constantinou-Kokotou V, Hadjipavlou-Litina D, Stephens D, Wong AC, Magrioti V, Moutevelis-Minakakis P, Baker SF, Dennis EA, Kokotos G. Six DA, et al. J Med Chem. 2007 Aug 23;50(17):4222-35. doi: 10.1021/jm0613673. Epub 2007 Aug 2. J Med Chem. 2007. PMID: 17672443

7

Lipidomics analysis of essential fatty acids in macrophages.

Quehenberger O, Armando A, Dumlao D, Stephens DL, Dennis EA. Quehenberger O, et al. Among authors: stephens dl. Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):123-9. doi: 10.1016/j.plefa.2008.09.021. Epub 2008 Nov 8. Prostaglandins Leukot Essent Fatty Acids. 2008. PMID: 18996688 Free PMC article.

8

2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides.

Barbayianni E, Stephens D, Grkovich A, Magrioti V, Hsu YH, Dolatzas P, Kalogiannidis D, Dennis EA, Kokotos G. Barbayianni E, et al. Bioorg Med Chem. 2009 Jul 1;17(13):4833-43. doi: 10.1016/j.bmc.2009.03.069. Epub 2009 May 3. Bioorg Med Chem. 2009. PMID: 19443224 Free PMC article.

9

Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release.

Yaksh TL, Kokotos G, Svensson CI, Stephens D, Kokotos CG, Fitzsimmons B, Hadjipavlou-Litina D, Hua XY, Dennis EA. Yaksh TL, et al. J Pharmacol Exp Ther. 2006 Jan;316(1):466-75. doi: 10.1124/jpet.105.091686. Epub 2005 Oct 3. J Pharmacol Exp Ther. 2006. PMID: 16203828

10

Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A2 enzymes.

Baskakis C, Magrioti V, Cotton N, Stephens D, Constantinou-Kokotou V, Dennis EA, Kokotos G. Baskakis C, et al. J Med Chem. 2008 Dec 25;51(24):8027-37. doi: 10.1021/jm800649q. J Med Chem. 2008. PMID: 19053783 Free PMC article.

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