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Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs.
Tribouillard-Tanvier D, Dos Reis S, Gug F, Voisset C, Béringue V, Sabate R, Kikovska E, Talarek N, Bach S, Huang C, Desban N, Saupe SJ, Supattapone S, Thuret JY, Chédin S, Vilette D, Galons H, Sanyal S, Blondel M. Tribouillard-Tanvier D, et al. Among authors: huang c. PLoS One. 2008 May 14;3(5):e2174. doi: 10.1371/journal.pone.0002174. PLoS One. 2008. PMID: 18478094 Free PMC article.
Mitochondrial NAD+ deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm.
Zhang J, Tang Y, Zhang S, Xie Z, Ma W, Liu S, Fang Y, Zheng S, Huang C, Yan G, Abudupataer M, Xin Y, Zhu J, Han W, Wang W, Shen F, Lai H, Liu Y, Ye D, Yu FX, Xu Y, Pan C, Wang C, Zhu K, Zhang W. Zhang J, et al. Among authors: huang c. Nat Cardiovasc Res. 2025 Jan 22. doi: 10.1038/s44161-024-00606-w. Online ahead of print. Nat Cardiovasc Res. 2025. PMID: 39843801
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