Chen J - Search Results

1

Lignan-rich sesame seed negates the tumor-inhibitory effect of tamoxifen but maintains bone health in a postmenopausal athymic mouse model with estrogen-responsive breast tumors.

Sacco SM, Chen J, Power KA, Ward WE, Thompson LU. Sacco SM, et al. Among authors: chen j. Menopause. 2008 Jan-Feb;15(1):171-9. doi: 10.1097/gme.0b013e3180479901. Menopause. 2008. PMID: 17545920

2

Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen.

Truan JS, Chen JM, Thompson LU. Truan JS, et al. Mol Nutr Food Res. 2010 Oct;54(10):1414-21. doi: 10.1002/mnfr.200900521. Mol Nutr Food Res. 2010. PMID: 20425756

3

Comparative effects of sesame seed lignan and flaxseed lignan in reducing the growth of human breast tumors (MCF-7) at high levels of circulating estrogen in athymic mice.

Truan JS, Chen JM, Thompson LU. Truan JS, et al. Nutr Cancer. 2012;64(1):65-71. doi: 10.1080/01635581.2012.630165. Epub 2011 Dec 2. Nutr Cancer. 2012. PMID: 22136581

4

Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF-7 xenografts in ovariectomized athymic nude mice.

Power KA, Saarinen NM, Chen JM, Thompson LU. Power KA, et al. Int J Cancer. 2006 Mar 1;118(5):1316-20. doi: 10.1002/ijc.21464. Int J Cancer. 2006. PMID: 16152607

5

Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model.

Power KA, Ward WE, Chen JM, Saarinen NM, Thompson LU. Power KA, et al. Bone. 2006 Jul;39(1):117-24. doi: 10.1016/j.bone.2005.12.015. Epub 2006 Feb 15. Bone. 2006. PMID: 16469549

6

Flaxseed and soy protein isolate, alone and in combination, differ in their effect on bone mass, biomechanical strength, and uterus in ovariectomized nude mice with MCF-7 human breast tumor xenografts.

Power KA, Ward WE, Chen JM, Saarinen NM, Thompson LU. Power KA, et al. J Toxicol Environ Health A. 2007 Nov;70(22):1888-96. doi: 10.1080/15287390701549179. J Toxicol Environ Health A. 2007. PMID: 17966060

7

Changes in biomarkers of estrogen receptor and growth factor signaling pathways in MCF-7 tumors after short- and long-term treatment with soy and flaxseed.

Power KA, Chen JM, Saarinen NM, Thompson LU. Power KA, et al. J Steroid Biochem Mol Biol. 2008 Nov;112(1-3):13-9. doi: 10.1016/j.jsbmb.2008.07.003. Epub 2008 Jul 25. J Steroid Biochem Mol Biol. 2008. PMID: 18703142

8

Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro.

Chen J, Thompson LU. Chen J, et al. Breast Cancer Res Treat. 2003 Jul;80(2):163-70. doi: 10.1023/A:1024513815374. Breast Cancer Res Treat. 2003. PMID: 12908819

9

Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice.

Chen J, Hui E, Ip T, Thompson LU. Chen J, et al. Clin Cancer Res. 2004 Nov 15;10(22):7703-11. doi: 10.1158/1078-0432.CCR-04-1130. Clin Cancer Res. 2004. PMID: 15570004

10

The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenograftsis attributed to both its lignan and oil components.

Wang L, Chen J, Thompson LU. Wang L, et al. Among authors: chen j. Int J Cancer. 2005 Sep 20;116(5):793-8. doi: 10.1002/ijc.21067. Int J Cancer. 2005. PMID: 15849746

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