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beta-tting on p63 as a metastatic suppressor.
Clohessy JG, Pandolfi PP. Clohessy JG, et al. Cell. 2009 Apr 3;137(1):28-30. doi: 10.1016/j.cell.2009.03.028. Cell. 2009. PMID: 19345184 Free article.
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC, Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R, Cognetti F, Scher HI, Pandolfi PP. Alimonti A, et al. Among authors: clohessy jg. J Clin Invest. 2010 Mar;120(3):681-93. doi: 10.1172/JCI40535. Epub 2010 Feb 8. J Clin Invest. 2010. PMID: 20197621 Free PMC article.
Pro-senescence therapy for cancer treatment.
Nardella C, Clohessy JG, Alimonti A, Pandolfi PP. Nardella C, et al. Among authors: clohessy jg. Nat Rev Cancer. 2011 Jun 24;11(7):503-11. doi: 10.1038/nrc3057. Nat Rev Cancer. 2011. PMID: 21701512 Review.
Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita.
Nachmani D, Bothmer AH, Grisendi S, Mele A, Bothmer D, Lee JD, Monteleone E, Cheng K, Zhang Y, Bester AC, Guzzetti A, Mitchell CA, Mendez LM, Pozdnyakova O, Sportoletti P, Martelli MP, Vulliamy TJ, Safra M, Schwartz S, Luzzatto L, Bluteau O, Soulier J, Darnell RB, Falini B, Dokal I, Ito K, Clohessy JG, Pandolfi PP. Nachmani D, et al. Among authors: clohessy jg. Nat Genet. 2019 Oct;51(10):1518-1529. doi: 10.1038/s41588-019-0502-z. Epub 2019 Sep 30. Nat Genet. 2019. PMID: 31570891 Free PMC article.
62 results