Senkal CE - Search Results

1

Mechanisms of ceramide-mediated repression of the human telomerase reverse transcriptase promoter via deacetylation of Sp3 by histone deacetylase 1.

Wooten-Blanks LG, Song P, Senkal CE, Ogretmen B. Wooten-Blanks LG, et al. Among authors: senkal ce. FASEB J. 2007 Oct;21(12):3386-97. doi: 10.1096/fj.07-8621com. Epub 2007 Jun 4. FASEB J. 2007. PMID: 17548428

2

Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas.

Koybasi S, Senkal CE, Sundararaj K, Spassieva S, Bielawski J, Osta W, Day TA, Jiang JC, Jazwinski SM, Hannun YA, Obeid LM, Ogretmen B. Koybasi S, et al. Among authors: senkal ce. J Biol Chem. 2004 Oct 22;279(43):44311-9. doi: 10.1074/jbc.M406920200. Epub 2004 Aug 17. J Biol Chem. 2004. PMID: 15317812 Free article.

3

Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function.

Sultan I, Senkal CE, Ponnusamy S, Bielawski J, Szulc Z, Bielawska A, Hannun YA, Ogretmen B. Sultan I, et al. Among authors: senkal ce. Biochem J. 2006 Jan 15;393(Pt 2):513-21. doi: 10.1042/BJ20051083. Biochem J. 2006. PMID: 16201965 Free PMC article.

4

Potent antitumor activity of a novel cationic pyridinium-ceramide alone or in combination with gemcitabine against human head and neck squamous cell carcinomas in vitro and in vivo.

Senkal CE, Ponnusamy S, Rossi MJ, Sundararaj K, Szulc Z, Bielawski J, Bielawska A, Meyer M, Cobanoglu B, Koybasi S, Sinha D, Day TA, Obeid LM, Hannun YA, Ogretmen B. Senkal CE, et al. J Pharmacol Exp Ther. 2006 Jun;317(3):1188-99. doi: 10.1124/jpet.106.101949. Epub 2006 Mar 1. J Pharmacol Exp Ther. 2006. PMID: 16510697

5

Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK.

Kitatani K, Idkowiak-Baldys J, Bielawski J, Taha TA, Jenkins RW, Senkal CE, Ogretmen B, Obeid LM, Hannun YA. Kitatani K, et al. Among authors: senkal ce. J Biol Chem. 2006 Dec 1;281(48):36793-802. doi: 10.1074/jbc.M608137200. Epub 2006 Oct 9. J Biol Chem. 2006. PMID: 17030510 Free article.

6

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells.

Baran Y, Salas A, Senkal CE, Gunduz U, Bielawski J, Obeid LM, Ogretmen B. Baran Y, et al. Among authors: senkal ce. J Biol Chem. 2007 Apr 13;282(15):10922-34. doi: 10.1074/jbc.M610157200. Epub 2007 Feb 15. J Biol Chem. 2007. PMID: 17303574 Free article.

7

Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas.

Senkal CE, Ponnusamy S, Rossi MJ, Bialewski J, Sinha D, Jiang JC, Jazwinski SM, Hannun YA, Ogretmen B. Senkal CE, et al. Mol Cancer Ther. 2007 Feb;6(2):712-22. doi: 10.1158/1535-7163.MCT-06-0558. Mol Cancer Ther. 2007. PMID: 17308067

8

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis.

Karahatay S, Thomas K, Koybasi S, Senkal CE, Elojeimy S, Liu X, Bielawski J, Day TA, Gillespie MB, Sinha D, Norris JS, Hannun YA, Ogretmen B. Karahatay S, et al. Among authors: senkal ce. Cancer Lett. 2007 Oct 18;256(1):101-11. doi: 10.1016/j.canlet.2007.06.003. Epub 2007 Jul 9. Cancer Lett. 2007. PMID: 17619081 Free PMC article. Clinical Trial.

9

Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling.

Mukhopadhyay A, Saddoughi SA, Song P, Sultan I, Ponnusamy S, Senkal CE, Snook CF, Arnold HK, Sears RC, Hannun YA, Ogretmen B. Mukhopadhyay A, et al. Among authors: senkal ce. FASEB J. 2009 Mar;23(3):751-63. doi: 10.1096/fj.08-120550. Epub 2008 Nov 21. FASEB J. 2009. PMID: 19028839 Free PMC article.

10

Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.

White-Gilbertson S, Mullen T, Senkal C, Lu P, Ogretmen B, Obeid L, Voelkel-Johnson C. White-Gilbertson S, et al. Oncogene. 2009 Feb 26;28(8):1132-41. doi: 10.1038/onc.2008.468. Epub 2009 Jan 12. Oncogene. 2009. PMID: 19137010 Free PMC article.

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