Birnbaum MJ - Search Results

1

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

Li X, Monks B, Ge Q, Birnbaum MJ. Li X, et al. Among authors: birnbaum mj. Nature. 2007 Jun 21;447(7147):1012-6. doi: 10.1038/nature05861. Epub 2007 Jun 6. Nature. 2007. PMID: 17554339

2

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.

Lu M, Wan M, Leavens KF, Chu Q, Monks BR, Fernandez S, Ahima RS, Ueki K, Kahn CR, Birnbaum MJ. Lu M, et al. Among authors: birnbaum mj. Nat Med. 2012 Feb 19;18(3):388-95. doi: 10.1038/nm.2686. Nat Med. 2012. PMID: 22344295 Free PMC article.

3

Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo.

Titchenell PM, Chu Q, Monks BR, Birnbaum MJ. Titchenell PM, et al. Among authors: birnbaum mj. Nat Commun. 2015 May 12;6:7078. doi: 10.1038/ncomms8078. Nat Commun. 2015. PMID: 25963408 Free PMC article.

4

Insulin Is Required to Maintain Albumin Expression by Inhibiting Forkhead Box O1 Protein.

Chen Q, Lu M, Monks BR, Birnbaum MJ. Chen Q, et al. Among authors: birnbaum mj. J Biol Chem. 2016 Jan 29;291(5):2371-8. doi: 10.1074/jbc.M115.677351. Epub 2015 Dec 14. J Biol Chem. 2016. PMID: 26668316 Free PMC article.

5

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.

Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, Chen H, Monks BR, Chen J, Rabinowitz JD, Birnbaum MJ. Titchenell PM, et al. Among authors: birnbaum mj. Cell Metab. 2016 Jun 14;23(6):1154-1166. doi: 10.1016/j.cmet.2016.04.022. Epub 2016 May 26. Cell Metab. 2016. PMID: 27238637 Free PMC article.

6

Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity.

Wan M, Easton RM, Gleason CE, Monks BR, Ueki K, Kahn CR, Birnbaum MJ. Wan M, et al. Among authors: birnbaum mj. Mol Cell Biol. 2012 Jan;32(1):96-106. doi: 10.1128/MCB.05806-11. Epub 2011 Oct 28. Mol Cell Biol. 2012. PMID: 22037765 Free PMC article.

7

Lack of AKT in adipocytes causes severe lipodystrophy.

Shearin AL, Monks BR, Seale P, Birnbaum MJ. Shearin AL, et al. Among authors: birnbaum mj. Mol Metab. 2016 May 13;5(7):472-479. doi: 10.1016/j.molmet.2016.05.006. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408773 Free PMC article.

8

Akt and CHIP coregulate tau degradation through coordinated interactions.

Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, Petrucelli L. Dickey CA, et al. Among authors: birnbaum mj. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3622-7. doi: 10.1073/pnas.0709180105. Epub 2008 Feb 21. Proc Natl Acad Sci U S A. 2008. PMID: 18292230 Free PMC article.

9

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.

Miller RA, Chu Q, Xie J, Foretz M, Viollet B, Birnbaum MJ. Miller RA, et al. Among authors: birnbaum mj. Nature. 2013 Feb 14;494(7436):256-60. doi: 10.1038/nature11808. Epub 2013 Jan 6. Nature. 2013. PMID: 23292513 Free PMC article.

10

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha.

Tuttle RL, Gill NS, Pugh W, Lee JP, Koeberlein B, Furth EE, Polonsky KS, Naji A, Birnbaum MJ. Tuttle RL, et al. Among authors: birnbaum mj. Nat Med. 2001 Oct;7(10):1133-7. doi: 10.1038/nm1001-1133. Nat Med. 2001. PMID: 11590437

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